Publications by authors named "H S Minnaar"
Background And Purpose: Radical surgery is the standard of care for early rectal cancer. However, alternative organ-preserving approaches are attractive, especially in frail or elderly patients as these avoid surgical complications. We have assessed the efficacy of sole Contact X-ray Brachytherapy (CXB) treatment in stage-1 rectal cancer patients who were unsuitable for or declined surgery.
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- The study examines the effectiveness of combining short course radiotherapy (SCRT) with contact X-Ray brachytherapy (CXB) for organ preservation in early stage rectal cancer patients, especially those unable to undergo chemotherapy.
- Analyzing data from 258 patients across five centers in the UK and Sweden, the results showed a high rate of complete clinical response, with 70% in the radiotherapy alone group and 97% after local excision, along with a low local relapse rate.
- The findings indicate that this treatment approach provides good palliative results and helps patients remain stoma-free, emphasizing the need for further research on quality of life post-treatment.
Legislation that governs the health and safety of communities near major-hazard installations in South Africa is largely based on existing legislation that had been developed in the United Kingdom and other European Union countries. The latter was developed as a consequence of several major human-induced technological disasters in Europe. The history of the evolution of health-and-safety legislation for the protection of vulnerable communities in European Union (EU) countries, France, Malaysia and the USA is explored through a literature survey.
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