The association between short-term exposure to ambient PM and hospitalization costs in patients with myocardial infarction: a hospital-based study.

Myocardial infarction (MI) ranks as one of the primary causes of global disabilities and disease deaths. The association between fine particulate matter (PM2.5) and MI has gained attention in recent years.

[Study of the occurrence of metabolic dysfunction-associated fatty liver disease in obstructive sleep apnea hypopnea syndrome and its risk factors].

To analyze the occurrence of metabolic dysfunction-associated fatty liver disease (MAFLD) and related inflammatory indicators in obstructive sleep apnea hypopnea syndrome (OSAHS) and explore the risk factors of MAFLD. A cross-sectional study. From January 2022 to October 2024,172 patients with sleep disorders were enrolled in the First Affiliated Hospital of Soochow University,including 38 patients with non-OSAHS,53 patients with mild OSAHS,37 patients with moderate OSAHS,and 44 patients with severe OSAHS.

Green revolution gene drives adaptation of Arabidopsis to the extremely high altitude.

To elucidate the process of adaptation, particularly the traits subject to natural selection and the molecular mechanisms underlying their natural variation, is one of the primary objectives of evolutionary biology. The uplifted landscape offers an excellent framework for understanding how organisms adapt to dramatic climatic gradients. To investigate the genetic basis of plant adaptation to the extremely high altitude, we first compared the genomic and phenotypic variations of two closely related Arabidopsis thaliana accessions from high altitude (Xizang, also known as "Tibet") and low altitude (Yunnan), respectively.

Absorbable Meek skin graft material transplantation: A preliminary experimental study.

Background: Wound closure is the core issue in treating patients with extensive burns. Allogeneic grafts can serve as a suitable temporary substitute in third-degree burns, and the Meek technique has provided encouraging outcomes in recent decades. However, whether allografts and the Meek technique could be used simultaneously so as to leverage the strengths of both has not been extensively examined.

Proximity to petrochemical industry and risk of childhood asthma occurrence.

Adverse effects on the respiratory system were associated with intensive petroleum-related industrial activities. The study aimed to assess the impact of petrochemical exposure on childhood asthma using various surrogate indices. A singleton birth cohort from 2004 to 2017 was conducted, leveraging two linked nationwide databases in Taiwan.

Long-term exposure to multiple air pollutants and risk of Parkinson's disease: a population-based multipollutant model study.

Background: Recent evidence suggests brain-first Parkinson's disease (PD) may start from the olfactory system, indicating potential inhalational exposure to causal agents. We investigated the impact of long-term exposure to various air pollutants on PD incidence using both single- and multi-pollutant models to account for interactions between pollutants.

Methods: This retrospective population study used data from Taiwan's National Health Insurance Research Database (2006 and 2018) and included individuals aged 40-65 without PD.

A de novo Gene Promotes Seed Germination Under Drought Stress in Arabidopsis.

The origin of genes from noncoding sequences is a long-term and fundamental biological question. However, how de novo genes originate and integrate into the existing pathways to regulate phenotypic variations is largely unknown. Here, we selected 7 genes from 782 de novo genes for functional exploration based on transcriptional and translational evidence.

Macrophages: Key players in diabetic wound healing.

In this editorial, we discuss the article by Wen published. Diabetic foot ulcers are prevalent and serious complications of diabetes, significantly impacting patients' quality of life and often leading to disability or death, thereby placing a heavy burden on society. Effective diabetic wound healing is hindered by an imbalance in macrophage polarization; many macrophages fail to transition from the pro-inflammatory M1 phenotype to the anti-inflammatory M2 phenotype, which is crucial for tissue remodelling and repair.

Temporal change in minimum mortality temperature under changing climate: A multicountry multicommunity observational study spanning 1986-2015.

Background: The minimum mortality temperature (MMT) or MMT percentile (MMTP) is an indicator of population susceptibility to nonoptimum temperatures. MMT and MMTP change over time; however, the changing directions show region-wide heterogeneity. We examined the heterogeneity of temporal changes in MMT and MMTP across multiple communities and in multiple countries.

Enantioselective 1,4-Borylamination via Copper-Catalyzed Cascade Hydroborylation and Hydroamination of Arylidenecyclopropanes.

Compounds bearing both boryl and amino groups at distal positions are invaluable synthons for synthesizing pharmaceuticals, drug candidates, and natural products, but their catalytic enantioselective synthesis remains rarely explored. We report the first enantioselective 1,4-borylamination reaction through a copper-catalyzed cascade hydroborylation and hydroamination of arylidenecyclopropanes. This reaction combines four readily available components in a highly chemo-, site-, and enantioselective fashion (>20:1 r.

[Expression and clinical significance of PIKFYVE gene in hepatocellular carcinoma analyzed based on TCGA database and experimental validation].

To investigate the expression and clinical significance of human FYVE finger-containing phosphoinositide kinase (PIKFYVE) in hepatocellular carcinoma (HCC) on the basis of cancer genome atlas (The cancer genome atlas, TCGA) database analysis and clinical samples experimental validation. Based on the data information of 424 clinical samples (including 374 cases of HCC tissues and 50 cases of nontumorous liver tissues) in the TCGA database, Cox regression analysis and Kaplan-Meier method were used to analyse the relationship between the PIKFYVE mRNA expression and the clinical characteristics, prognosis for survival of HCC patients. The relationship between the PIKFYVE gene and immune cell infiltration was examined by correlation analysis between the PIKFYVE gene and 24 immune cells.

Synthesis of polyaniline tannate-modified carbon nanotubes by oxidative copolymerization as highly efficient corrosion inhibitors for mild steel in HCl solution.

Corrosion is a prevalent issue in industrial production, directly impacting the production process and causing severe damages. To mitigate this problem, corrosion inhibitors are highly desired. Herein, a novel type of nano corrosion inhibitor, referred to as PTCNT, was synthesized through an oxidative copolymerization method utilizing aniline, ammonium persulfate (APS), and tannic acid (TA)-modified multiwalled carbon nanotubes (MWCNTs).

[Characteristics of Spatial and Temporal Changes in Carbon Stocks in the Middle and Upper Reaches of the Huaihe River Basin and Future Multi-scenario Simulation Prediction].

The Huaihe River Basin is located in the north-south climate transition zone of China. The change of carbon storage in this area is of great significance for predicting the future ecological protection, mitigating climate change, and maintaining sustainable development of the Huaihe River Basin. The middle and upper reaches of Huaihe River Basin （above Bengbu station） were taken as the research area.

Temperature-mortality associations by age and cause: a multi-country multi-city study.

Background: Heterogeneity in temperature-mortality relationships across locations may partly result from differences in the demographic structure of populations and their cause-specific vulnerabilities. Here we conduct the largest epidemiological study to date on the association between ambient temperature and mortality by age and cause using data from 532 cities in 33 countries.

Methods: We collected daily temperature and mortality data from each country.

Pancreatic agenesis and altered m6A methylation in the pancreas of PDX1-mutant cynomolgus macaques.

As an essential transcriptional activator, plays a crucial role in pancreatic development and β-cell function. Mutations in the gene may lead to type 4 maturity-onset diabetes of the young (MODY4) and neonatal diabetes mellitus. However, the precise mechanisms underlying MODY4 remain elusive due to the paucity of clinical samples and pronounced differences in pancreatic architecture and genomic composition between humans and existing animal models.