Publications by authors named "Ghinea R"
Machine-Learning-Based Spectral Modeling: A Biomimetic Guide for Enhancing Esthetics.
J Esthet Restor Dent
December 2024
Objective: To provide guidelines and means for optimal coverage and distribution of computer models with 1-10 clusters, designed based on an in vivo extensive dental colorimetric database and compare the findings with some reputable shade guides.
Materials And Methods: The Fuzzy C-Means (FCM) algorithm was used to optimize the tab position in the CIELAB color space, while MATLAB Fuzzy Logic was used to implement the codes. A minimization process was performed to fine-tune the cluster centers, minimizing Coverage Error (CE) and Maximum Error (ME).
Article Synopsis
- Early post-transplant hyperglycemia (EPTH) is linked to several negative health outcomes for kidney transplant patients, including increased risk of readmissions and the development of post-transplant diabetes mellitus (PTDM).
- A study analyzed the effects of dedicated endocrine care (DEC) compared to routine care (RC) on glycemic control in kidney transplant recipients over an eight-day period.
- Results showed that patients under DEC had better blood glucose management, with lower average blood glucose levels, a higher likelihood of receiving insulin when necessary, and fewer instances of low blood sugar compared to those receiving RC.
Color Ranges and Distribution of Human Teeth: A Prospective Clinical Study.
J Esthet Restor Dent
October 2024
Introduction: This study investigated the in vivo color range of human teeth using a research-grade noncontact spectroradiometer, analyzing the effects of gender, age, ethnicity, and lifestyle factors, including diet, smoking, and oral hygiene.
Materials And Methods: A total of 1004 participants were recruited at two research sites and stratified by gender, age, and ethnicity, and data on their dietary and oral habits were collected. Noninvasive color measurements of an upper central incisor were performed using a spectroradiometer and a fiber-coupled Xe-Arc light source.
Article Synopsis
- - Kidney issues are common in systemic sclerosis (SSc), with about 50% of patients showing altered kidney function, and serious cases (scleroderma renal crisis or SRC) occurring in roughly 20% of patients.
- - SRC is mostly seen in patients with the diffuse cutaneous systemic sclerosis (dcSSc) subtype and those with anti-RNA polymerase III antibodies, but the introduction of ACE inhibitors has significantly reduced related mortality rates from 78% to between 30% and 36%.
- - Despite improvements, many patients still progress to end-stage renal disease (ESRD) requiring treatments like renal replacement therapies, with kidney transplant rates remaining low at 3-8% for SRC patients and 4
Background: Individualizing induction therapy based on immunological risk is crucial for optimizing outcomes in kidney transplantation.
Methods: A retrospective analysis included 157 first live-donor non-sensitized kidney transplant recipients (KTRs). Within this cohort, 96 individuals exhibited low human leukocyte antigen (HLA) matching (5-6 HLA mismatches).
Objectives: To evaluate the influence of microstructure and chemical composition on the optical properties of CAD-CAM lithium disilicate glass-ceramics.
Methods: Samples (n = 5; 1.0 mm thickness) of shades A1, A2, and A3 were fabricated from CAD-CAM ceramic blocks (Ivoclar Vivadent): IPS e.
Objective: To evaluate the perceptibility and acceptability CIEDE2000 (K:K:K) thresholds for lightness, chroma and hue differences in dentistry.
Method: A Python-based program was developed to conduct a psychophysical experiment based on visual assessments of computer-simulated images of human teeth. The experiment was performed on a calibrated display.
Objective: To assess the prediction accuracy of recent optical and numerical models for the spectral reflectance and color of monolithic samples of dental materials with different thicknesses.
Methods: Samples of dental resin composites of Aura Easy Flow (Ae1, Ae3 and Ae4 shades) and Estelite Universal Flow Super Low (A1, A2, A3, A3.5, A4 and A5 shades) with thicknesses between 0.
Living kidney donation has increased significantly, but little is known about the post-donation health-related quality of life (HRQoL) of non-directed donors (NDs) vs. directed donors (DDs). We thus examined the outcomes of 112 living kidney donors (82 NDs, 30 DDs).
View Article and Find Full Text PDFBackground: Since 2014, as part of a priority program within the Israeli Transplant Law, additional points were given to waitlisted candidates with donor cards. We assessed the impact on deceased donor kidney allocation.
Methods: This study enrolled all patients older than 18 y who underwent deceased donor kidney transplantation (January 2016-December 2019).
Article Synopsis
- The study aimed to identify the acceptable color difference thresholds in dental materials based on their chromaticity, utilizing two observer groups: dentists and laypersons.
- A panel of 40 participants evaluated 144 pairs of dental composites, categorized by low, medium, and high chroma, in controlled lighting to determine the acceptable thresholds using statistical methods.
- Results showed that acceptability thresholds varied significantly among chroma groups, indicating that observers preferred less colorful (low chroma) samples, which has implications for quality control in dental practices and research.
Introduction: Metrics for posttransplant immune monitoring to prevent over or under immunosuppression in renal transplant recipients (RTRs) are lacking.
Methods: We surveyed 132 RTRs, 38 in the first year posttransplant and 94 >1-year posttransplant, to study the clinical expression of immunosuppressive therapy. A questionnaire administered to these RTRs was divided into physical (Q physical) and mental (Q mental) symptoms.
Purpose: This secondary analysis further analyzed variations in the 50:50% perceptibility and acceptability thresholds (PT and AT, respectively) pertaining to light, medium, and dark tooth-colored specimen sets.
Methods: Primary raw data from the original study was retrieved. Visual thresholds (Perceptibility - PT and Acceptability - AT) were analyzed among the three specimen sets - light, medium, and dark.
Usually, dentin and enamel shades are layered in dental restorations with the purpose of mimicking the natural appearance of teeth. The main objective of this study was to develop and assess accuracy of a color-prediction method for both monolithic and layered dental resin-based composites with varying shades and under different illuminants. A total of 15 different shades of VITAPAN Excell, VITAPAN Dentine and VITA Physiodens as well as VITA Enamel of five different thicknesses (0.
View Article and Find Full Text PDFA full comprehension of colorimetric relationships within and between teeth is key for aesthetic success of a dental restoration. In this sense, hyperspectral imaging can provide point-wise reliable measurements of the tooth surface, which can serve for this purpose. The aim of this study was to use a hyperspectral imaging system for the colorimetric characterization of 4 in-vivo maxillary anterior teeth and to cross-check the results with similar studies carried out with other measuring systems in order to validate the proposed capturing protocol.
View Article and Find Full Text PDFObjective: The aim of this study was to assess the accuracy of a Principal Components Analysis (PCA)-based method for reflectance reconstruction and color estimation of layered dental resin-based composites with different thicknesses.
Method: Bi-layered samples of different clinically relevant thicknesses were created using shades of VITAPAN Excell (VE), VITAPAN Dentine (VD) and VITA Physiodens (VP), combined with their corresponding enamel shades. Spectral reflectance of all samples was measured over a black background using a non-contact spectroradiometer with CIE 45∕0 geometry.
Article Synopsis
- Obesity among kidney transplant recipients is linked to higher risks of mortality and graft failure, prompting a study comparing outcomes between obese (BMI > 30 kg/m²) and non-obese patients, involving 1403 patients from a single center.
- The study found that obese patients had worse survival rates and higher incidence of graft complications, particularly with deceased donor (DD) transplants, indicating a need for closer consideration of metabolic health in these patients.
- Researchers suggest that weight loss strategies, including the use of GLP-1 inhibitors and possible bariatric surgery, could help improve outcomes for obese patients awaiting kidney transplants.
Objectives: This study aims to evaluate in vivo the color agreement between natural teeth and dental shade guides by means of visual and instrumental coverage error ([Formula: see text]) index.
Materials And Methods: The color of the middle third of 735 incisors was visually determined by two evaluators using the Vita Classical (VC) and Vita 3D Master (V3DM) shade guides. The color match between the natural tooth and the shade tab was rated as poor (P), good (G), or optimum (O) by each observer.
An impaired humoral response to full dose of BNT162b2 vaccine was observed in renal transplant recipients (RTR). To reveal predictors for humoral response to third vaccine, patients were stratified to positive (N = 85) and negative (N = 14) response groups based on receptor-binding domain (RBD) IgG ≥1.1 and neutralizing antibodies (NA) ≥ 16 dilution versus RBD IgG <1.
View Article and Find Full Text PDFObjective: Define the color of anterior teeth of a selected population and correlate it (by using coverage error [CE] and the frequency of best match) with the final color of all possible enamel-dentine combinations of three different resin composite systems.
Materials And Methods: Color of 636 vital unrestored anterior teeth (central incisors, lateral incisors and canines; n = 212) and disk specimens (12 mm diameter, varying thickness) corresponding to enamel-dentin combinations of all available enamel (0.5 mm and 1.
Objective: To assess accuracy of reflectance reconstruction and color estimation of different dental materials with varying thicknesses using Principal Component Analysis (PCA).
Method: A1, A2, A3, A3.5, B2, C2 and D2 shades and 5 thicknesses (within 0.
Objective: To perform a comprehensive review of the use of artificial intelligence (AI) and machine learning (ML) in dentistry, providing the community with a broad insight on the different advances that these technologies and tools have produced, paying special attention to the area of esthetic dentistry and color research.
Materials And Methods: The comprehensive review was conducted in MEDLINE/PubMed, Web of Science, and Scopus databases, for papers published in English language in the last 20 years.
Results: Out of 3871 eligible papers, 120 were included for final appraisal.
Unlabelled: With scarce organ supply, a selection of suitable elderly candidates for transplant is needed, as well as auditing the long-term outcomes after transplant. We conducted an observational cohort study among our patient cohort >60 years old with a long follow up. (1).
View Article and Find Full Text PDFBackground: Data about SARS-CoV-2 vaccines efficacy in renal transplant recipients (RTR) are lacking.
Methods: To reveal predictors for humoral response to BNT162b2 vaccine among RTR, patients were divided into positive (N = 42) and negative (N = 78) response groups based on receptor-binding domain (RBD) immunoglobulin G (IgG) ≥1.1 and neutralizing antibodies (NA) ≥16 dilution versus RBD IgG <1.
Objective: To analyze translucency variations among four different contemporary esthetic ceramic systems having different shades and thicknesses.
Material And Methods: Ceramic specimens having different shades and translucencies were tested: leucite reinforced glass-ceramic (ECAD), conventional feldspathic ceramic (Noritake), zirconia reinforced lithium silicate glass-ceramic (Suprinity) and hybrid ceramic (Enamic). Specimens of 0.