Impact of deep vein thrombosis on adolescent athletes: Navigating an invisible disability.

Background: Injury in adolescent athletes that threatens their sport participation can result in a sense of identity loss during critical years for identity development, creating the potential for significant mental health challenges. The specific effect of deep vein thrombosis (DVT) in this vulnerable population has not been characterized.

Purpose: To describe the impact of DVT diagnosis, treatment, and long-term complications on the mental well-being of athletes who sustained a DVT during adolescence and to identify strategies to improve the quality of care for these patients.

Serum leptin is not correlated with body fat in severe food restriction.

Leptin is an adipose-derived hormone with established roles in energy balance that can impact the response to refeeding after malnutrition. Although the amount of circulating leptin has traditionally been associated with the amount of adipose tissue, controversy exists as to whether this relationship is constant in both humans and animals and over a wide range of body composition. Our objective was to evaluate whether the leptin - body fat ratio is constant in the range of healthy to low body mass in female Wistar rats.

A notable case of nephrosis.

How a boy of 10 developed nephrosis more than 60 years ago, how he came to be seen by Sir Frederic Still with interesting later consequences, how his nephrosis cleared following measles, and how all this led to his becoming a distinguished paediatrician is told in a case history based on the diary kept by the boy's mother.

Assessment of total body fat in infancy from skinfold thickness measurements.

A formula is given, allowing a value for total body fat to be calculated from skinfold thickness measurements at two sites (subscapular and triceps), in conjunction with nine body dimensions. For newborn infants total body fat so calculated accorded satisfactorily with published data from cadaver analyses. The formula has been tentatively applied to infants up to the age of 40 weeks, and to preterm infants.

IgA deficiency in one of identical twins.

A disease resembling childhood coeliac disease occurred in one of identical twins. When the twins were investigated at the age of 23 the initial diagnosis could not be substantiated but the twin who had been ill had selective IgA deficiency. Differences dating from early infancy may have been a result of the discordance for IgA deficiency.

Size of adipose cells in infancy.

Seventy-three samples of adipose tissue from 59 infants, aged from 25 weeks' gestation to 18 months of age, were obtained at necropsy, or at operations, or by needle biopsy. Adipose cell size was measured by microscopy. During fetal life the mean cell diameter increases from about 40 mum at 25 weeks' gestation to 50-80 mum at term.

Body fat of British and Dutch infants.

The fatty acids in the body fat of 41 British and 37 Dutch infants between birth and 1 year were determined. At birth linoleic acid contributed 1-3% of the total fatty acids of the body fat in infants in both countries. By one month its proportion in the fat of the Dutch infants was about 25% and by four months 32-37%; in the fat of the British infants it was never more than 3%.

Predictive factors in open myelomeningocele with special reference to sensory level.

A total of 113 cases of open myelomeningocele operated on shortly after birth were followed up and the 80 survivors (71%) were assessed one and a quarter to seven and a half years later. Their disability was classified in terms of mobility, intelligence, continence, and major complications; these when combined provided an assessment of overall disability. The overall disability of the survivors was minimal in 6%, moderate in 40%, severe in 39%, and very severe in 15%.

A growth chart for premature and other infants.

The growth chart covers the period from 28 weeks of fetal life to age 2 years, and allows weight, length, and head circumference to be charted. The time scale is logarithmic, providing the convenience of an extended scale for the earlier months of life, and giving the graphs an approximately linear form. Separate charts for boys and girls are provided, with 10th, 50th, and 90th centiles.

Hyaline membrane disease. II. Lung lecithin.

The lecithin content of lung, together with its surface tension properties, were determined in 34 stillbirths, and 61 neonatal deaths. Lecithin content ranged widely from 1·5 to 18·6% of dry lung tissue. In 24 cases the `palmitic-lecithin' was also measured; it formed 44-79% of the total lecithins.

Hyaline membrane disease. I. Cellular changes.

Cellular changes were studied in 1 μ thick sections of lungs from 84 perinatal deaths, including 44 with hyaline membrane disease (HMD). The presence or absence of osmiophilic granules was related to surface tension measurements in 69 cases. The presence of numerous granules usually indicated normal surfactant and their absence a lack.