New progress in HBV control and the cascade of health care for people living with HBV in China: evidence from the fourth national serological survey, 2020.

Background: Since 1992, when recombinant hepatitis B vaccine was introduced in China, government health officials have used nationally representative serological surveys to monitor progress in prevention and control of hepatitis B. In 2020, we conducted the fourth seroepidemiological survey, which for the first time included medical evaluation of the clinical status of HBsAg positive subjects over the age of 15 and their medical management. We report survey results in comparison with the three previous surveys.

Neural Signals Associated with Orienting Response and Arousal Inhibition in Concealed Information Test.

Recent theory suggests that both the orienting response and arousal inhibition play roles in the effect of the concealed information test (CIT). However, the neural signatures associated with these two processes remain unclear. To address this issue, participants were motivated to either conceal or reveal crime-related stimulus during CIT while EEG was recorded.

Dynamic functional network connectivity in patients with a mismatch between white matter hyperintensity and cognitive function.

Objective: White matter hyperintensity (WMH) in patients with cerebral small vessel disease (CSVD) is strongly associated with cognitive impairment. However, the severity of WMH does not coincide fully with cognitive impairment. This study aims to explore the differences in the dynamic functional network connectivity (dFNC) of WMH with cognitively matched and mismatched patients, to better understand the underlying mechanisms from a quantitative perspective.

miR-153 promotes neural differentiation by activating the cell adhesion/Ca signaling pathway and targeting ion channel activity in HT-22 cells by bioinformatic analysis.

MicroRNAs have been studied extensively in neurodegenerative diseases. In a previous study, miR-153 promoted neural differentiation and projection formation in mouse hippocampal HT-22 cells. However, the pathways and molecular mechanism underlying miR-153induced neural differentiation remain unclear.

Coexistence of Ferroelectricity and Ferromagnetism in Atomically Thin Two-Dimensional CrS/WS Vertical Heterostructures.

Two-dimensional (2D) heterostructures with ferromagnetism and ferroelectricity provide a promising avenue to miniaturize the device size, increase computational power, and reduce energy consumption. However, the direct synthesis of such eye-catching heterostructures has yet to be realized up to now. Here, we design a two-step chemical vapor deposition strategy to growth of CrS/WS vertical heterostructures with atomically sharp and clean interfaces on sapphire.

A bat biomimetic model for scenario recognition using echo Doppler information.

The flying bat can detect the difference in Doppler frequency between its echolocation transmission signal and the echoes in its surroundings, enabling it to distinguish between various scenarios effectively. By examining the bio-sonar biomimetic model of a flying bat that uses echo Doppler information for environmental recognition, it may enhance the scene recognition capability of human ultrasound sonar during movement. The paper establishes a three-dimensional clutter model of the flying state of bat bio-sonar for bats emitting constant frequency signals.

Robust multiferroic in interfacial modulation synthesized wafer-scale one-unit-cell of chromium sulfide.

Multiferroic materials offer a promising avenue for manipulating digital information by leveraging the cross-coupling between ferroelectric and ferromagnetic orders. Despite the ferroelectricity has been uncovered by ion displacement or interlayer-sliding, one-unit-cell of multiferroic materials design and wafer-scale synthesis have yet to be realized. Here we develope an interface modulated strategy to grow 1-inch one-unit-cell of non-layered chromium sulfide with unidirectional orientation on industry-compatible c-plane sapphire.

Effect of the oxygenic groups on activated carbon on its hemocompatibility.

In this research, the effect of the oxygenic groups on activated carbon on its hemocompatibility was studied by liquid-phase oxidation to introduce oxygenic groups on its surface and subsequent heat treatment under a nitrogen environment to remove these groups. Hemocompatibility was assessed through coagulation, hemolysis, platelet adhesion, and protein adsorption using rabbit blood samples. Results showed that an increasing presence of oxygenic groups improved hemocompatibility, evidenced by enhanced coagulation, reduced hemolysis, better platelet adhesion, and decreased fetal bovine serum protein adsorption.

Epidemiological characteristics and risk factors of syphilis among blood donors in Huzhou.

Objective: To investigate the epidemiological characteristics and risk factors for syphilis in Huzhou City, and to provide data to support the design of more effective health counselling and screening measures for blood donors.

Methods: A retrospective study was conducted to analyse the demographic characteristics and seropositivity of syphilis among blood donors from 2019 to 2021. The differences in the serological status of syphilis among different populations under different demographic factors were compared, and conditional logistic regression analysis was used to identify the risk factors for syphilis.

Ozone therapy for high-grade glioma: an overview.

High-grade gliomas (grades III and IV) are highly malignant and aggressive brain tumors that present significant treatment challenges. Despite advances in surgery, chemotherapy, and radiation therapy, the prognosis for patients with glioma remains poor, with a median overall survival (mOS) range of 9-12 months. Therefore, exploring new and effective therapeutic strategies to improve glioma prognosis is of utmost importance and ozone therapy is a viable option.

Diatomite-Templated Synthesis of Single-Atom Cobalt-Doped MoS /Carbon Composites to Boost Sodium Storage.

2D transition metal dichalcogenides (TMDCs) and single-atom catalysts (SACs) are promising electrodes for energy conversion/storage because of the layered structure and maximum atom utilization efficiency. However, the integration of such two type materials and the relevant sodium storage applications remain daunting challenges. Here, an ingenious diatomite-templated synthetic strategy is designed to fabricate single-atom cobalt-doped MoS /carbon (SA Co-MoS /C) composites toward the high-performance sodium storage.

FeN Coordination Induced Ultralong Lifetime of Sodium-Ion Battery with the Cycle Number Exceeding 65 000.

Sodium-ion batteries (SIBs) have received increasing attention because of their appealing cell voltages and cost-effective features. However, the atom aggregation and electrode volume variation inevitably deteriorate the sodium storage kinetics. Here a new strategy is proposed to boost the lifetime of SIB by synthesizing sea urchin-like FeSe /nitrogen-doped carbon (FeSe /NC) composites.

Interisland-Distance-Mediated Growth of Centimeter-Scale Two-Dimensional Magnetic FeO Arrays with Unidirectional Domain Orientations.

Two-dimensional (2D) nanosheet arrays with unidirectional orientations are of great significance for synthesizing wafer-scale single crystals. Although great efforts have been devoted, the growth of atomically thin magnetic nanosheet arrays and single crystals is still unaddressed. Here we design an interisland-distance-mediated chemical vapor deposition strategy to synthesize centimeter-scale atomically thin FeO arrays with unidirectional orientations on mica.

Room-Temperature Magnetoelectric Coupling in Atomically Thin ε-Fe O.

2D multiferroics with magnetoelectric coupling combine the magnetic order and electric polarization in a single phase, providing a cornerstone for constructing high-density information storages and low-energy-consumption spintronic devices. The strong interactions between various order parameters are crucial for realizing such multifunctional applications, nevertheless, this criterion is rarely met in classical 2D materials at room-temperature. Here an ingenious space-confined chemical vapor deposition strategy is designed to synthesize atomically thin non-layered ε-Fe O single crystals and disclose the room-temperature long-range ferrimagnetic order.

Interfacial Coupling SnSe /SnSe Heterostructures as Long Cyclic Anodes of Lithium-Ion Battery.

Tin selenide (SnSe ) is considered a promising anode of the lithium-ion battery because of its tunable interlayer space, abundant active sites, and high theoretical capacity. However, the low electronic conductivity and large volume variation during the charging/discharging processes inevitably result in inadequate specific capacity and inferior cyclic stability. Herein, a high-throughput wet chemical method to synthesize SnSe /SnSe heterostructures is designed and used as anodes of lithium-ion batteries.

Two-dimensional multiferroic material of metallic p-doped SnSe.

Two-dimensional multiferroic materials have garnered broad interests attributed to their magnetoelectric properties and multifunctional applications. Multiferroic heterostructures have been realized, nevertheless, the direct coupling between ferroelectric and ferromagnetic order in a single material still remains challenging, especially for two-dimensional materials. Here, we develop a physical vapor deposition approach to synthesize two-dimensional p-doped SnSe.

Study on the Relationship Between Peritoneal Dialysis Ultrafiltration Failure and Aquaporin 1, Aquaporin 3, and Vascular Endothelial Growth Factor A Expression.

Introduction: The aim of this study was to investigate the expression of aquaporin 1 (AQP-1), AQP-3 and vascular endothelial growth factor A (VEGF-A) in peritoneal tissues of patients without kidney disease, chronic kidney disease at stages 5 (CKD 5) and patients on prolonged peritoneal dialysis with ultrafiltration failure (PDUFF), and elucidate the possible mechanism of peritoneal dialysis ultrafiltration failure.

Methods: Peritoneal specimens were collected from the following patient groups at Xianju People's hospital: CKD 5, PD-UFF and normal control groups. Routine staining and immunohistochemical analyses were performed on samples obtained from the three groups.

Intestinal Haemorrhage and Colitis Induced by Treatment With Osimertinib for Non-Small-Cell Lung Carcinoma: A Case Report.

Osimertinib is recommended either as the first-line therapy for sensitizing EGFR-mutations (FLAURA trial) or at progression to first-/second-generation EGFR inhibitors in the presence of resistance mutation T790M (AURA 3 study). It can effectively improve the prognosis of patients with NSCLC with manageable adverse reactions. Among adverse events, intestinal haemorrhage is rare and requires extensive study on its potential lethality.

MiR-6924-5p-rich exosomes derived from genetically modified Scleraxis-overexpressing PDGFRα(+) BMMSCs as novel nanotherapeutics for treating osteolysis during tendon-bone healing and improving healing strength.

Osteolysis at the tendon-bone interface can impair pullout strength during tendon-bone healing and lead to surgery failure, but the effects of clinical treatments are not satisfactory. Mesenchymal stem cell (MSC)-derived exosomes have been used as potent and feasible natural nanocarriers for drug delivery and have been proven to enhance tendon-bone healing strength, indicating that MSC-derived exosomes could be a promising therapeutic strategy. In this study, we explored Scleraxis (Scx) dynamically expressed in PDGFRα(+) bone marrow-derived mesenchymal stem cells (BMMSCs) during natural tendon-bone healing.

Effects of serine palmitoyltransferase inhibition by myriocin in ad libitum-fed and nutrient-restricted ewes.

The fungal isolate myriocin inhibits serine palmitoyltransferase and de novo ceramide synthesis in rodents; however, the effects of myriocin on ceramide concentrations and metabolism have not been previously investigated in ruminants. In our study, 12 non-lactating crossbred ewes received an intravenous bolus of myriocin (0, 0.1, 0.

Fatigue life analysis for 6061-T6 aluminum alloy based on surface roughness.

Surface condition is one of the dominant factors affecting fatigue life. Considering the complexity of surface condition, a relatively efficient and economic approach based on surface reconstruction and interpolation method was proposed. The effect of surface roughness on the fatigue life of 6061-T6 aluminum alloy is studied to analyze the fatigue life by surface roughness parameters.