Publications by authors named "Farzane Khalili"

Expression of concern for 'Investigation of the biological activity, mechanical properties and wound healing application of a novel scaffold based on lignin-agarose hydrogel and silk fibroin embedded zinc chromite nanoparticles' by Reza Eivazzadeh-Keihan , , 2021, , 17914-17923, https://doi.org/10.1039/D1RA01300A.

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Article Synopsis
  • * The scaffold demonstrated low toxicity (less than 13%) and minimal hemolytic effects (1.67%), along with significant antibacterial properties, as evidenced by low biofilm formation.
  • * Mice treated with the scaffold showed almost complete wound healing within five days, while structural analyses confirmed that the addition of silk fibroin and ZnCrO improved the composite's mechanical properties and elasticity.
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Based on the promising biomedical developments in wound healing strategies, herein, a new nanobiocomposite scaffold was designed and presented by incorporation of carboxymethyl cellulose hydrogels prepared using epichlorohydrin as a cross-linking agent (CMC hydrogel), a natural silk fibroin (SF) protein, and magnesium hydroxide nanoparticles (Mg(OH) NPs). Biological evaluation of the CMC hydrogel/SF/Mg(OH) nanobiocomposite scaffold was conducted via in vitro cell viability assays and in vivo assays, red blood cell hemolysis, and antibiofilm assays. Considering the cell viability percentage of Hu02 cells (84.

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In this study, a nanobiocomposite scaffold was fabricated by combining sodium alginate, polyvinyl alcohol, silk fibroin and magnesium hydroxide nanorods. The structural characteristics and properties of the scaffold were identified by field emission scanning electron microscope (FE-SEM), thermogravimetric analysis (TGA), Fourier-transformed infrared (FT-IR) and energy dispersive X-Ray (EDX) analyses. To introduce the application, biocompatibility, mechanical properties and biological activity of the scaffold were obtained.

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