Magnetically retrievable carbon-wrapped CNT/Ni nanospheres as efficient catalysts for nitroaromatic reduction.

We present a facile strategy for synthesizing magnetically retrievable carbon-wrapped CNT/Ni nanospheres (C-wrapped CNT/Ni) that enhance the catalytic performance of metals for environmental pollutant reduction. Structural and compositional analyses using X-ray diffraction (XRD), Raman spectroscopy, energy-dispersive X-ray spectroscopy (EDS), and field emission scanning electron microscopy (FESEM) confirmed the phase purity, morphology, and structure of the C-wrapped CNT/Ni. XRD, Raman, and EDS data validate the formation of the nanospheres, while FESEM images reveal uniform Ni nanospheres wrapped with a carbon layer through interconnected, evenly dispersed CNTs.

Substrate-Induced Structural Dynamics and Evolutionary Linkage of Siderophore-Iron ABC Transporters of .

: ATP-binding cassette (ABC) transporters are prominent drug targets due to their highly efficient trafficking capabilities and their significant physiological and clinical roles. Gaining insight into their biophysical and biomechanistic properties is crucial to maximize their pharmacological potential. : In this study, we present the biochemical and biophysical characterization, and phylogenetic analysis of the domains of () ABC transporters: the exporter Rv1348 (IrtA) and the importer system Rv1349-Rv2895c (IrtB-Rv2895c), both involved in siderophore-mediated iron uptake.

Genotyping and Characterizing to Reveal Genetic Diversity and Multiplicity of Infection by Merozoite Surface Proteins 1 and 2 ( and ) and Glutamate-Rich Protein () Genes.

Resistance to current antimalarial drugs is steadily increasing, and new drugs are required. Drug efficacy trials remain the gold standard to assess the effectiveness of a given drug. The World Health Organization (WHO)'s recommendation for the optimal duration of follow-up for assessing antimalarial efficacy is a minimum of 28 days.

Incidence, and maternal and neonatal outcomes following pregnancy-associated colorectal cancer: A population-based linked data study.

Aim: The study aimed to describe the incidence of pregnancy-associated colorectal cancer (PACRC) in New South Wales (NSW), Australia, and to examine the perinatal outcomes of women with PACRC and their babies.

Methods: A population-based cohort study was conducted using linked data from NSW. The study group comprised all women diagnosed with colorectal cancer during pregnancy (gestational CRC) or postpartum (postpartum CRC).

Dennd2c Negatively Controls Multinucleation and Differentiation in Osteoclasts by Regulating Actin Polymerization and Protrusion Formation.

Osteoclasts are bone-resorbing multinucleated giant cells formed by the fusion of monocyte/macrophage lineages. Various small GTPases are involved in the multinucleation and differentiation of osteoclasts. However, the roles of small GTPases regulatory molecules in osteoclast differentiation remain unclear.

Autophagy Regulator Rufy 4 Promotes Osteoclastic Bone Resorption by Orchestrating Cytoskeletal Organization via Its RUN Domain.

Rufy4, a protein belonging to the RUN and FYVE domain-containing protein family, participates in various cellular processes such as autophagy and intracellular trafficking. However, its role in osteoclast-mediated bone resorption remains uncertain. In this study, we investigated the expression and role of the gene in osteoclasts using small interfering RNA (siRNA) transfection and gene overexpression systems.

Rapid synthesis of cobalt manganese phosphate by microwave-assisted hydrothermal method and application as positrode material in supercapatteries.

Electrochemical energy storage devices with high specific capacity are of utmost important for the next-generation electronic devices. Supercapatteries (SCs) are highly demanded energy storage devices nowadays as these bridge the low energy supercapacitors and low power batteries. Herein, we report a rapid synthesis of cobalt manganese phosphate (COMAP) by microwave-assisted hydrothermal method and facile fabrication of SCs using electrodes comprising of COMAP as positrode material.

Sublingual Fast-Dissolving Thin Films of Loratadine: Characterization, In Vitro and Ex Vivo Evaluation.

Loratadine (LOR) is a second-generation antihistamine that exhibits a low and variable oral bioavailability (10-40%) and delayed onset owing to poor solubility and an extensive first-pass effect. Therefore, in light of the clinical need, the main goal of the present study was to develop sublingual fast-dissolving thin films of LOR-citric acid co-amorphous systems (LOR-CAs) with the aim of eliciting a faster onset and improving the bioavailability. We formulated sublingual fast-dissolving thin films of LOR by a film-casting technique using hydrophilic polymers like hydroxypropyl methylcellulose (HPMC E15), polyvinyl pyrrolidone K30 (PVP K30), and hydroxypropyl cellulose EL (HPC-EF) and citric acid as a pH modulator, while glycerin served as a plasticizer.

Water as Dual-Function Plasticizer and Cosolvent in Gel Electrolytes for Dye-Sensitized Solar Cells.

This study presents a novel approach to developing eco-friendly dye-sensitized solar cells (DSSCs) using natural and renewable materials for gel polymer electrolytes (GPEs), reducing reliance on unsustainable solvents. Water is added to polar aprotic solvents, specifically ethylene carbonate/propylene carbonate (EC/PC), across various mass fractions (0:100 to 100:0). An amphiphilic hydroxypropyl cellulose (HPC) natural polymer is employed to formulate GPEs within this water-EC/PC cosolvent system, achieving successful gelation up to 50:50 mass fractions.

Designing nano-heterostructured nickel doped tin sulfide/tin oxide as binder free electrode material for supercapattery.

New generation of electrochemical energy storage devices (EESD) such as supercapattery is being intensively studied as it merges the ideal energy density of batteries and optimal power density of supercapacitors in a single device. A multitude of parameters such as the method of electrodes preparation can affect the performance of supercapattery. In this research, nickel doped tin sulfide /tin oxide (SnS@Ni/SnO) heterostructures were grown directly on the Ni foam and subjected to different calcination temperatures to study their effect on formation, properties, and electrochemical performance through X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), and electrochemical tests.

Efficacy and Safety of Valganciclovir in Congenital Cytomegalovirus Infection with Isolated Intrahepatic Cholestasis: A Randomized Controlled Trial.

Purpose: Cytomegalovirus (CMV) infection affects the hepatic, neurologic, hematopoietic, respiratory, gastrointestinal, and other organs, resulting in a high mortality rate and long-term sequelae. It may cause acute or chronic hepatitis, or even lead to hepatic cirrhosis. Valganciclovir (VGCV) is an effective, safe, and well-tolerated treatment for congenital CMV infection, without any serious adverse effects.

The global burden of overweight-obesity and its association with economic status, benefiting from STEPs survey of WHO member states: A meta-analysis.

Introduction: The World Health Organization (WHO) 2030 agenda for Sustainable Development Goals (SDGs target 3.4) identifies non-communicable diseases (NCDs) as a key challenge for sustainable development. As one of the major NCD risks, here, we estimated the prevalence of overweight/obesity in adults and assessed country-economic variations using -analysis.

Microbial infection among SARS-COV-2-infected patients in a COVID-19-dedicated tertiary care hospital of Bangladesh: a cross-sectional study.

This study aimed to determine patterns of respiratory, blood-borne and uropathogenic microbial pathogens among SARS-CoV-2-infected patients in a COVID-19-(coronavirus disease 2019) dedicated tertiary care hospital in Dhaka, Bangladesh. This was a cross-sectional study. In a COVID-19-dedicated tertiary care hospital in Dhaka, Bangladesh, conducted from March to June 2021.

Knowledge, acceptance and concerns regarding COVID-19 vaccination among pregnant women on the east coast of Peninsular Malaysia: A cross-sectional study.

Introduction: This prospective cross-sectional study, conducted from 1 April 2022 to 31 October 2022, aimed to assess the knowledge, acceptance and concerns regarding COVID-19 vaccination among pregnant women visiting the Obstetrics and Gynaecology Department of Hospital Universiti Sains Malaysia.

Methods: The study included all pregnant women aged >18 years. Sociodemographic data, information related to COVID-19 and vaccination and information on the knowledge, acceptance and concerns regarding COVID-19 vaccination were collected using a validated questionnaire.

Synergy between psychological impact and biochemical manifestation of stress among the COVID-19 pandemic-affected population.

Objective: Due to the COVID-19 pandemic, many countries around the world experienced an unprecedented increase in stress in the general population. Even after normal life has been reestablished, the new normal is punctuated by severely impacted vulnerable groups. Stress-associated symptoms display an intricate relationship with biochemical modulations, which coordinate the stress response.

Box-Behnken Design-Based Optimization and Evaluation of Lipid-Based Nano Drug Delivery System for Brain Targeting of Bromocriptine.

Bromocriptine (BCR) presents poor bioavailability when administered orally because of its low solubility and prolonged first-pass metabolism. This poses a significant challenge in its utilization as an effective treatment for managing Parkinson's disease (PD). The utilization of lipid nanoparticles can be a promising approach to overcome the limitations of BCR bioavailability.