Informing Risk Hotspots and Critical Mitigations for Rainstorms Using Machine Learning: Evidence from 268 Chinese Cities.

Climate change is exacerbating rainstorms, increasing the risk of flooding and threatening urban sustainability, which could undermine climate action. Here, we propose a machine learning-based framework to assess heterogeneous risks and identify critical mitigation measures for rainstorms across 268 Chinese cities. Nighttime light serves as a proxy for urban functionality, and meteorological, socio-economic, and infrastructural factors are incorporated to uncover underlying impact mechanisms.

 (Gesneriaceae), a new species in the karst landforms of Guizhou Province, China.

X.X.Bai & F.

The association between neighborhood social vulnerability and community-based rehabilitation after stroke.

Background: Timely rehabilitative care is vital for functional recovery after stroke. Social determinants may influence access to and use of post-stroke care but have been inadequately explored. The study examined the relationship between the Social Vulnerability Index (SVI) and community-based rehabilitation utilization.

Evaluation of Clinical Effect of Acupuncture on Chronic Prostatitis: Meta Analysis.

This study aims to evaluate the clinical efficacy of acupuncture and moxibustion in CP treatment and assess the quality of clinical literature. Controlled clinical trials (CCT) and randomized controlled trials (RCTs) from PubMed, Web of Science, NLM, CNKI, and Wanfang (January 2003 to January 2023) were analyzed. Relevant data were extracted and statistically analyzed using RevMan 5.

Unveiling miRNA30b's Role in Suppressing ADAM12 to Combat Triple-Negative Breast Cancer.

Triple-negative breast cancer, a subtype of breast cancer, is characterized by a poor prognosis. Recent studies have shown that miRNA30b acts as an oncogene and is vital for the proliferation of malignancies across various systems. This study aimed to elucidate the impact of miRNA30b on the proliferation, migration, and invasion capabilities of breast cancer cells .

The clinical value of local consolidative therapy for oligo-residual disease in PD-1/PD-L1 inhibitors-treated non-small cell lung cancer.

Background: Few real-world studies exist regarding the clinical value of local consolidative therapy (LCT) for oligo-residual disease (ORD) in NSCLC patients treated with immune checkpoint inhibitors. Therefore, we retrospectively evaluated whether LCT could improve the prognosis of NSCL patients with ORD after effective first-line PD-1/PD-L1 inhibitors treatment.

Methods: A total of 132 patients with metastatic NSCLC who had received first-line PD-1/PD-L1inhibitors-based systemic treatment and developed ORD (defined as residual tumors limited to three organs and five lesions) were included.

LPCAT3 regulates the proliferation and metastasis of serous ovarian cancer by modulating arachidonic acid.

Background: Lysophosphatidylcholine acyltransferase 3 (LPCAT3) promotes ferroptosis through the incorporating polyunsaturated fatty acids into membrane phospholipids, however, its role in serous ovarian cancer remains unclear. Here explored cancer proliferation and metastasis after modulating LPCAP3.

Methods: LPCAT3 protein in ovarian cancer tissues was detected using bioinformatic and immunohistoche mical assays.

Early Neurological Deterioration in Acute Ischemic Minor Stroke Patients with Large Vessel Occlusion Following Intravenous Thrombolysis.

Objective: Early identification of risk factors associated with early neurological deterioration (END) in patients with acute minor stroke and large vessel occlusion (LVO) receiving intravenous thrombolysis (IVT) could assist in formulating treatment decisions.

Methods: Consecutive patients with acute minor stroke and LVO were extracted from a single-center prospective database spanning from January 2020 to December 2023. END was defined as an increase of ≥4 points in the National Institutes of Health Stroke Scale score from baseline or ≥2 points in any single National Institutes of Health Stroke Scale item, within 24 hours of IVT.

Several new combinations from previous to (Gesneriaceae).

The recently published species, , is transferred here to the recently re-circumscribed genus, . Two varieties, recently assigned to , have been raised to the rank of species. Their Chinese vernacular names are also revised and provided here.

Comparative chloroplast genomes analysis of nine Primulina (Gesneriaceae) rare species, from karst region of southwest China.

Guizhou Province is one of the most important karst regions of southwest China, with 22 Primulina species. These species are highly habitat-specialized and dependent on the soils of the karst region, and many inter-species classifications are unclear. Therefore, studying the chloroplast genomes and estimating the divergence times of there species can not only provide a better understanding of interspecific relationships but also help to know the species speciation and divergence in the karst environment.

Research on Safety of Aero-Engine Oil Pipe Under Heating Conditions Based on Fluid-Solid Thermal Coupling.

This paper examines the safety of aero-engine pipelines under different heating conditions. Based on the fire test standard documents, a model of an aero-engine oil pipe was constructed, and its safety under heating conditions that meet the standard was analyzed using fluid-solid thermal coupling. The pipe material was stainless steel 1Cr18Ni9Ti, and the oil inside the pipeline was China RP-3 kerosene.

A broadband hyperspectral image sensor with high spatio-temporal resolution.

Hyperspectral imaging provides high-dimensional spatial-temporal-spectral information showing intrinsic matter characteristics. Here we report an on-chip computational hyperspectral imaging framework with high spatial and temporal resolution. By integrating different broadband modulation materials on the image sensor chip, the target spectral information is non-uniformly and intrinsically coupled to each pixel with high light throughput.

Understanding the Relationship Between Adverse Medication Use and Falls Among Older Patients Receiving Home Medical Care: OHCARE study.

Previous studies suggest older patients with multiple health conditions and medications may experience adverse interactions, leading to negative outcomes. However, there's limited research on this in older adults receiving home medical care. This study assesses whether polypharmacy is linked to falls or other clinical outcomes.

(Gesneriaceae), a Peltate-Leaved New Species From the Dry-Hot Valley of the Jinsha River Basin, Yunnan, China.

A peltate-leaved new species, Z. Xie & H. H.

Key environmental parameters and numerical prediction model of jellyfish bloom in Qingchuan Bay Nuclear Power Plant, China.

In recent years, there has been a notable increase in cooling water intake blockage caused by marine organism blooms at coastal nuclear power plants worldwide, resulting in shutdowns of nuclear power plants and large economic losses. A sizable portion of these incidents were caused by blooms from jellyfish, a planktonic invertebrate with a unique growth pattern. Suitable external conditions are conducive to the rapid growth of jellyfish, and blooms can occur within a few days.

A comprehensive risk assessment of microplastics in soil, water, and atmosphere: Implications for human health and environmental safety.

Microplastics (MPs) are pervasive across ecosystems, likely posing significant environmental and health risks based on more and more evidence. In this study, we searched through the Web of Science Core Collection and obtained 1039 papers for visualization and analysis. In order to discuss the chemical composition, migration, transformation and potential risk of MPs, 135 sets of relevant data in soil, water, and atmosphere were collected in China as a typical region, which is a hotspot region for investigation of MPs.

YTHDF3 modulates the progression of breast cancer cells by regulating FGF2 through mA methylation.

Introduction: Breast cancer (BC) is a prevailing malignancy among women, and its inconspicuous development contributes significantly to mortality. The RNA N6-methyladenosine (mA) modification represents an emerging mechanism for gene expression regulation, with the active involvement of the YTH N6-methyladenosine RNA binding protein 3 (YTHDF3) in tumor progression across multiple cancer types. Nonetheless, its precise function in breast cancer necessitates further investigation.

Migration and availability of Ni and Cd in industrial soils under different leaching conditions: Insights from DGT and DIFS models.

Rainfall runoff can mobilize heavy metals in industrial soils, posing environmental risks. The mobility and distribution of heavy metals in different industrial soil layers are often overlooked. This study employed dynamic leaching experiments in layered soil columns with DGT (the diffusive gradients in thin films) measurements and DIFS (DGT-induced fluxes in soils and sediments) model to describe the migration, availability, and resupply ability of metals at different depths in surface and deep soil columns of industrial soils.

Research trends related to emergence agitation in the post-anaesthesia care unit from 2001 to 2023: A bibliometric analysis.

Background: Emergence agitation (EA) is a behavioural disturbance encountered during the recovery phase of patients following general anaesthesia. It is characterised by restlessness, involuntary limb movements, and drainage tube withdrawal and may significantly harm patients and medical staff. The mechanism of EA has not been fully understood and is still a challenging subject for researchers.

SHP2-Triggered Endothelial Cell Activation Fuels Estradiol-Independent Endometrial Sterile Inflammation.

Sterile inflammation occurs in various chronic diseases due to many nonmicrobe factors. Examples include endometrial hyperplasia (EH), endometriosis, endometrial cancer, and breast cancer, which are all sterile inflammation diseases induced by estrogen imbalances. However, how estrogen-induced sterile inflammation regulates EH remains unclear.

China's progress in synergetic governance of climate change and multiple environmental issues.

Advancing the synergetic control of climate change and environmental crisis is crucial for achieving global sustainable development goals. This study evaluates synergetic governance levels over climate change and four environmental issues at the provincial level in China from 2009 to 2020. Our findings reveal significant progress in China's coordinated efforts to mitigate carbon emissions, reduce air pollutants, and conserve water resources.

Predictive performance of [F]F-fibroblast activation protein inhibitor (FAPI)-42 positron emission tomography/computed tomography (PET/CT) in evaluating response of recurrent or metastatic gastrointestinal stromal tumors: complementary or alternative to [F]fluorodeoxyglucose (FDG) PET/CT?

Background: Accurately and promptly predicting the response of gastrointestinal stromal tumors (GISTs) to targeted therapy is essential for optimizing treatment strategies. However, some fractions of recurrent or metastatic GISTs present as non-FDG-avid lesions, limiting the value of [F]fluorodeoxyglucose positron emission tomography/computed tomography ([F]FDG PET/CT) in treatment evaluation. This study evaluated the efficacy of [F]F-fibroblast activation protein inhibitor (FAPI)-42 [F]FAPI-42) PET/CT for assessing the treatment response in recurrent or metastatic GISTs, in comparison to [F]FDG PET/CT and explores a model integrating PET/CT imaging and clinical parameters to optimize the clinical use of these diagnostic tools.

Measuring climate change perception in China using mental images: A nationwide open-ended survey.

Current knowledge about public climate change perception mainly covers belief, concern, and attitudes. However, how this discourse is interpreted using individuals' own frame of reference remains largely unknown, particularly in many large emitters from non-Annex I countries such as China. This study, for the first time, performs a nationwide open-ended survey covering 4,037 respondents and collected 12,100 textual answers.

Serum Uric Acid Levels Associated with Outcomes of Neurodegenerative Disorders and Brain Health: Findings from the UK Biobank.

Background: The relationship between serum uric acid (SUA) levels and brain-related health remains uncertain.

Objectives: This study aimed to investigate the relationship between SUA levels and some neurodegenerative disorders and brain structure.

Design: A longitudinal study.