[Detergent enzymes: has the risk of occupational sensitization disappeared?].

Occupational allergy to enzyme detergents had almost disappeared by the use of preventive measures, both individually and in industries. The occurrence of 8 new cases of asthma in a detergent factory has led to a prospective clinical and aetiological enquiry. Although there was no documentation using the specific provocation test or by measuring respiratory function whilst at work, the occupational character of this asthma seemed possible after taking a history.

Single brain metastasis of non-small cell lung carcinoma. Study of survival among 54 patients.

We studied 54 patients treated for non-small cell lung carcinoma with single brain metastasis presenting between 1980 and 1985. Better survival was obtained in cases of patients presenting a fair neurological condition who were treated by surgery. Histological condition and date of onet of metastasis had no significant influence on survival.

[A case of Carrington's chronic eosinophilic pneumonia associated with bronchocentric granulomatosis in an asthmatic patient].

A case of Carrington's chronic eosinophilic pneumonia associated with bronchocentric granulomatosis in a young asthmatic woman is reported. Among the numerous forms of "eosinophilic lung", the characteristic features of these two diseases in asthmatic patients are briefly described. Concerning the association, the authors have found that some authors suggest a common nosological framework with many transitional forms.

[Anaplastic small-cell bronchial carcinoma of the composite type].

The authors report an anatomico-clinical case (with ultrastructural study) of bronchial anaplastic carcinoma with composite, triple differentiation oat-cell subtype. The patient underwent early surgical excision followed by radiotherapy and chemotherapy. With the help of data from the literature concerning this composite subtype which suggests new theories on the histogenesis of bronchial cancer, the authors emphasize the value of surgical treatment for this unusual subtype of anaplastic carcinoma.

T-lymphocyte subsets in pleural fluids: discrimination according to traditional and monoclonal antibody-defined markers.

T-lymphocyte subpopulations in pleural fluid and in peripheral blood from 17 patients admitted for pleural effusion were identified by E-rosette formation and delineated by monoclonal antibodies OKT3 (peripheral T-cells), OKT4 (helper/inducer cells), and OKT8 (suppressor/cytotoxic cells). We studied 13 patients with specified pleural diseases (tuberculosis, malignancies, connective tissue diseases, congestive heart failure) and 4 patients with non-specified pleural diseases. Our findings showed that the percentage of T-cells increases in pleural fluid versus peripheral blood whatever the diagnosis is, and that these T-cells are predominantly helper/inducer cells.

[Accidental poisoning by volatile hydrocarbons in children (apropos of 57 cases)].

Most of the accidentally intoxicated children who are admitted into hospital have swallowed volatile hydrocarbons. The ingested products are either aliphatic hydrocarbons, whether white spirit or petrol, or aromatic hydrocarbons. We have collected informations upon 57 children admitted into the pediatric department of The American Memorial Hospital in Reims, from 1973 to 1982.