Publications by authors named "Dong Ni"

The inherent variability of lesions poses challenges in leveraging AI in 3D automated breast ultrasound (ABUS) for lesion detection. Traditional methods based on single scans have fallen short compared to comprehensive evaluations by experienced sonologists using multiple scans. To address this, our study introduces an innovative approach combining the multi-view co-attention mechanism (MCAM) with unsupervised contrastive learning.

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Background: Early diagnosis of cleft lip and palate (CLP) requires a multiplane examination, demanding high technical proficiency from radiologists. Therefore, this study aims to develop and validate the first artificial intelligence (AI)-based model (CLP-Net) for fully automated multi-plane localization in three-dimensional(3D) ultrasound during the first trimester.

Methods: This retrospective study included 418 (394 normal, 24 CLP) 3D ultrasound from 288 pregnant woman between July 2022 to October 2024 from Shenzhen Guangming District People's Hospital during the 11-13 weeks of pregnancy.

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Background: Most existing deep learning-based registration methods are trained on single-type images to address same-domain tasks, resulting in performance degradation when applied to new scenarios. Retraining a model for new scenarios requires extra time and data. Therefore, efficient and accurate solutions for cross-domain deformable registration are in demand.

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Interactive segmentation allows active user participation to enhance output quality and resolve ambiguities. This may be especially indispensable to medical image segmentation to address complex anatomy and customization to varying user requirements. Existing approaches often encounter issues such as information dilution, limited adaptability to diverse user interactions, and insufficient response.

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Neurofeedback, when combined with cognitive reappraisal, offers promising potential for emotion regulation training. However, prior studies have predominantly relied on functional magnetic resonance imaging, which could impede its clinical feasibility. Furthermore, these studies have primarily focused on reducing negative emotions while overlooking the importance of enhancing positive emotions.

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Prostate cancer (PCa) poses a significant threat to men's health, with early diagnosis being crucial for improving prognosis and reducing mortality rates. Transrectal ultrasound (TRUS) plays a vital role in the diagnosis and image-guided intervention of PCa. To facilitate physicians with more accurate and efficient computer-assisted diagnosis and interventions, many image processing algorithms in TRUS have been proposed and achieved state-of-the-art performance in several tasks, including prostate gland segmentation, prostate image registration, PCa classification and detection and interventional needle detection.

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Fetal pose estimation in 3D ultrasound (US) involves identifying a set of associated fetal anatomical landmarks. Its primary objective is to provide comprehensive information about the fetus through landmark connections, thus benefiting various critical applications, such as biometric measurements, plane localization, and fetal movement monitoring. However, accurately estimating the 3D fetal pose in US volume has several challenges, including poor image quality, limited GPU memory for tackling high dimensional data, symmetrical or ambiguous anatomical structures, and considerable variations in fetal poses.

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Shallow biogenic gas is crucial in global warming and carbon cycling. Considering the knowledge gap in the understanding of methanogenesis and metabolic mechanisms within shallow groundwater systems, we investigated Quaternary shallow biogenic gas resources from the Hetao Basin in North China, which were previously underexplored. We systematically analyzed the genesis of gas and formation water, microbial communities, methanogenic processes, and pathways using geochemistry, genomics, and transcriptomics.

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Article Synopsis
  • The study aims to enhance the diagnosis of mitral valve prolapse (MVP) by using an automated approach that combines multi-view echocardiography and deep learning, addressing limitations of traditional methods.
  • Researchers trained two types of deep learning models (view-specific and view-agnostic) on echocardiographic data, achieving high diagnostic accuracy for both fibroelastic deficiency (FED) and Barlow's disease (BD).
  • The results suggest that this AI-driven diagnostic method significantly improves efficiency and accuracy, indicating its potential for future clinical applications in diagnosing heart valve diseases.
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Segmentation of the fetal and maternal structures, particularly intrapartum ultrasound imaging as advocated by the International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) for monitoring labor progression, is a crucial first step for quantitative diagnosis and clinical decision-making. This requires specialized analysis by obstetrics professionals, in a task that i) is highly time- and cost-consuming and ii) often yields inconsistent results. The utility of automatic segmentation algorithms for biometry has been proven, though existing results remain suboptimal.

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To effectively capture and explain complex, nonlinear relationships within bicycle crash frequency data and account for unobserved heterogeneity simultaneously, this study proposes a new hybrid framework that combines the Random Forest-based SHapley Additive exPlanations (RF-SHAP) method with a random parameter negative binomial regression model (RPNB). First, four machine learning algorithms, including random forest (RF), support vector machine (SVM), gradient boosting machine (GBM), and Extreme Gradient Boosting (XGBoost), were compared for variable importance calculation. The RF algorithm, demonstrating the best performance, was selected and integrated into an interpretable machine learning-based method (i.

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The existence of internal and external heterogeneity has been established by numerous studies across various fields, including transportation and safety analysis. The findings from these studies underscore the complexity of crash data and the multifaceted nature of risk factors involved in accidents. However, most studies consider the effects of unobserved heterogeneity from one perspective -- either within clusters (internal) or between clusters (external) -- and do not investigate the biases from both simultaneously on crash frequency analysis.

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Background: No universally recognized transperineal ultrasound parameters are available for evaluating stress urinary incontinence. The information captured by commonly used perineal ultrasound parameters is limited and insufficient for a comprehensive assessment of stress urinary incontinence. Although bladder neck motion plays a major role in stress urinary incontinence, objective and visual methods to evaluate its impact on stress urinary incontinence remain lacking.

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Article Synopsis
  • The study aimed to set standard ranges for measuring the brain markers of babies in the womb during the first three months of pregnancy and created a new AI tool to do this automatically.
  • Researchers looked at ultrasound images of 4,233 healthy pregnant women and analyzed 10 important brain features of the babies.
  • The AI tool was super fast, measuring in just 0.49 seconds, and was very accurate, matching human measurements really well and helping find abnormal cases 100% of the time.
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Article Synopsis
  • Depression is increasingly recognized as a significant global psychological issue, with traditional detection methods criticized for their inefficiency and subjective nature.
  • A new framework called the Audio, Video, and Text Fusion-Three Branch Network (AVTF-TBN) integrates auditory, visual, and textual data for more accurate depression risk assessment through a multimodal approach.
  • Experimental results show that the AVTF-TBN model performs effectively in detecting depression risk, with metrics like F1 Score of 0.78, Precision of 0.76, and Recall of 0.81, highlighting the importance of sensor-based data in mental health evaluations.*
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Arrhythmia is a major cardiac abnormality in fetuses. Therefore, early diagnosis of arrhythmia is clinically crucial. Pulsed-wave Doppler ultrasound is a commonly used diagnostic tool for fetal arrhythmia.

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Background: Left ventricular opacification (LVO) improves the accuracy of left ventricular ejection fraction (LVEF) by enhancing the visualization of the endocardium. Manual delineation of the endocardium by sonographers has observer variability. Artificial intelligence (AI) has the potential to improve the reproducibility of LVO to assess LVEF.

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Objective: To develop an algorithm for the automated localization and measurement of levator hiatus (LH) dimensions (AI-LH) using 3-D pelvic floor ultrasound.

Methods: The AI-LH included a 3-D plane regression model and a 2-D segmentation model, which first achieved automated localization of the minimal LH dimension plane (C-plane) and measurement of the hiatal area (HA) on maximum Valsalva on the rendered LH images, but not on the C-plane. The dataset included 600 volumetric data.

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(Z)-alkenes are useful synthons but thermodynamically less stable than their (E)-isomers and typically more difficult to prepare. The synthesis of 1,4-hetero-bifunctionalized (Z)-alkenes is particularly challenging due to the inherent regio- and stereoselectivity issues. Herein we demonstrate a general, chemoselective and direct synthesis of (Z)-2-butene-1,4-diol monoesters.

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Objectives: To develop predictive nomograms based on clinical and ultrasound features and to improve the clinical strategy for US BI-RADS 4A lesions.

Methods: Patients with US BI-RADS 4A lesions from 3 hospitals between January 2016 and June 2020 were retrospectively included. Clinical and ultrasound features were extracted to establish nomograms CE (based on clinical experience) and DL (based on deep-learning algorithm).

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Lesion segmentation in ultrasound images is an essential yet challenging step for early evaluation and diagnosis of cancers. In recent years, many automatic CNN-based methods have been proposed to assist this task. However, most modern approaches often lack capturing long-range dependencies and prior information making it difficult to identify the lesions with unfixed shapes, sizes, locations, and textures.

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Background: This study presents CUPID, an advanced automated measurement software based on Artificial Intelligence (AI), designed to evaluate nine fetal biometric parameters in the mid-trimester. Our primary objective was to assess and compare the CUPID performance of experienced senior and junior radiologists.

Materials And Methods: This prospective cross-sectional study was conducted at Shenzhen University General Hospital between September 2022 and June 2023, and focused on mid-trimester fetuses.

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Thyroid nodule classification and segmentation in ultrasound images are crucial for computer-aided diagnosis; however, they face limitations owing to insufficient labeled data. In this study, we proposed a multi-view contrastive self-supervised method to improve thyroid nodule classification and segmentation performance with limited manual labels. Our method aligns the transverse and longitudinal views of the same nodule, thereby enabling the model to focus more on the nodule area.

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Complicated deformation problems are frequently encountered in medical image registration tasks. Although various advanced registration models have been proposed, accurate and efficient deformable registration remains challenging, especially for handling the large volumetric deformations. To this end, we propose a novel recursive deformable pyramid (RDP) network for unsupervised non-rigid registration.

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