Unraveling Complexity: Delving into a Novel Pigmented Epithelioid Melanocytoma Case.

Pigmented epithelioid melanocytoma (PEM) is a rare and diagnostically challenging skin neoplasm. Differentiating this lesion from melanoma is challenging due to overlapping clinical, histopathological, and immunohistochemical features. Some PEMs have a benign course, while others may be associated with more aggressive behaviour and have potential for local recurrence or distant metastasis.

Wavefront-guided pupilloplasty in patients following penetrating keratoplasty: Optimizing results.

Purpose: To describe the role of wavefront-guided pupilloplasty in improving visual quality and wavefront parameters in post-keratoplasty patients with pathologically irregular, mydriatic pupils.

Methods: A total of 13 eyes of post-penetrating keratoplasty patients with pathologically irregular mydriatic pupil were included in this prospective interventional study. Preoperative wavefront analysis was done with the actual pupil size, and predicted wavefront values were analyzed by setting the postoperative pupil size to 2 mm.

Adaptation and Validation of the Sydney Swallow Questionnaire into Kannada (KSSQ).

Self-rating questionnaires are necessary to quantify the impairment and the impact of impairment on the quality of life, provided that these questionnaires are delivered in the patient's native language. There are no questionnaires to assess the symptom severity of oropharyngeal dysphagia in Kannada-speaking individuals. The Sydney Swallow Questionnaire (SSQ) is one such explicit tool to assess the symptoms of dysphagia, especially among patients with oropharyngeal dysphagia.

Probiotic and Functional Attributes of Yeasts Isolated from Different Traditional Fermented Foods and Products.

Though numerous bacteria have been used as probiotics by industries, at present, Saccharomyces boulardii and Saccharomyces cerevesiae are the only yeast probiotics which are industrially exploited. In view of this, yeast probiotics were isolated from traditional fermented foods and products collected from different parts of Karnataka, India. In this work, we have studied the probiotic attributes of ten yeast isolates isolated from different traditionally fermented foods and products.

Wunderlich Syndrome: A Rare Case Associated with Bleeding Renal Angiomyolipoma (AML).

Renal angiomyolipoma (AML) is a benign mesenchymal tumor composed of fat, smooth muscle, and blood vessels. It represents 1-3% of solid renal tumors. Despite the benign nature of this tumor, it can be aggressive with locoregional extension.

Physicochemical cell disruption of sp. for recovery of polyhydroxyalkanoates: future bioplastic for sustainability.

Polyhydroxybutyrate (PHB) is known for wide applications, biocompatibility, and degradability; however, it cannot be commercialized due to conventional recovery using solvents. The present study employed mechanical cell-disruption methods, such as Pestle and mortar, sonication, and glass bead vortexing, for solvent-free extraction of PHA from sp. Different time intervals were set for grinding (5, 10, 15 min), sonicating (1, 3 and 5 min), and vortexing (2, 5 and 8 g glass beads with 5, 10 and 15 min each) hence studying their effect on cell lysis to release PHA.

Changing spectrum of primary pyomyositis in North India.

Recent data have demonstrated the changing epidemiology of primary pyomyositis worldwide. Our hospital-based retrospective study investigated the clinical and microbiological spectrum of primary pyomyositis between 2013 and 2021 in PGIMER (Chandigarh), India. Over a quarter had predisposing conditions, mainly diabetes mellitus and immunosuppressive therapy.

An Unusual Case of Post-partum Native Tricuspid Valve Infective Endocarditis.

Native valve infective endocarditis during pregnancy or the peripartum period is a rare entity with significant morbidity and mortality. Rheumatic heart disease was previously considered a significant risk factor, changing to intravenous drug abuse in recent decades. We hereby report a case of tricuspid native valve endocarditis complicating the peri-partum period in a young female without underlying traditional risk factors, who improved with medical therapy alone.

Hemophagocytic Lymphohistiocytosis due to Disseminated Histoplasmosis in a Patient with HIV Infection.

Hemophagocytic lymphohistiocytosis is usually considered a rapidly progressive fatal illness with poor outcomes. It is of two types: primary or familial and secondary. In patients with HIV, opportunistic infections are the secondary triggers of HLH.

Cross-Cultural Adaptation and Validation of the Language Experience and Proficiency Questionnaire Into Kannada.

Purpose: As there are no questionnaires to assess the experience and proficiency of bilingual/multilingual Kannada speakers, this study aimed to adapt and validate the Language Experience and Proficiency Questionnaire (LEAP-Q) into the Kannada language cross-culturally.

Method: A nonrandomized, prospective cross-sectional design with purposive sampling was used in the study. The cross-cultural adaptation was performed using a standard guideline for developing the questionnaire.

Antifungal activity of probiotic strain MYSN7 against .

The primary objective of this study was to assess the probiotic attributes and antifungal activity of lactic acid bacteria (LAB) against the fungus, . Among the 20 isolates screened for their antifungal attributes, isolate MYSN7 showed strong antifungal activity and was selected for further analysis. The isolate MYSN7 exhibited potential probiotic characteristics, having 75 and 70% survival percentages in pH3 and pH2, respectively, 68.

Probiotics and their postbiotics for the control of opportunistic fungal pathogens: A review.

During past twenty years the opportunistic fungal infections have been emerging, causing morbidity and mortality. The fungi belonging to and others cause severe opportunistic fungal infections. Among these and cause majority of the diseases.

Azaneylylidene-based tetradentate Schiff base as a new "ON-OFF" fluorescent probe for the detection of Cu(II) ion: Synthesis, characterization and real sample analysis.

Herein we describe the synthesis of Cu sensor, 2,2'-((1E,1'E)-((4-chloro-1,2-phenylene)bis(azaneylylidene))bis(methane-ylylidene))bis(4-bromophenol) (CPMB) and characterization using various spectral and analytical techniques. CPMB exhibited high selectivity towards Cu ions via fluorescence quenching mechanism, which combined the character of high selectivity towards Cu assay even in the presence of other common metal ions such as Cu, Al, Co, Ni, Mn, Zn Pb Cd, Fe, Hg, Mg and Fe (30 μM) ethanol-water (1:9 v/v) system. Upon the addition of the solution of Cu ions to CPMB, the complexation of Cu with CPMB leads to the immediate formation of light green color, indicating that CPMB can act as simple colorimetric sensor, particularly for Cu in the presence of most interfering metal ions in ethanol-water medium.

Empirical intravenous aciclovir therapy in a suspected case of acute encephalitis.

Herpes simplex encephalitis is the most common cause of sporadic viral encephalitis worldwide but presents as a diagnostic challenge at many settings due to its non-specific symptoms, which can be easily mistaken for systemic infection or metabolic encephalopathy. It has diverse range of presentations from fever, altered sensorium, nausea, vomiting, meningismus to seizures, neurological deficits and coma in advanced stages. It is associated with significant morbidity and mortality if treatment is delayed or inadequate.

Role of bone marrow examination in pyrexia of unknown origin.

A stepwise approach is essential to evaluating pyrexia of unknown origin (PUO). When other investigations are negative, bone marrow examination is a valuable diagnostic tool in PUO. It is particularly helpful in patients with involvement of reticuloendothelial organs (e.

Characterisation of broad-spectrum phiKZ like jumbo phage and its utilisation in controlling multidrug-resistant Pseudomonas aeruginosa isolates.

The emergence of highly virulent multidrug-resistant P. aeruginosa has become increasingly evident among hospital-acquired infections and has raised the need for alternative therapies. Phage therapy can be one such alternative to antibiotic therapy to combat multidrug-resistant pathogenic bacteria, but this requires the availability of phages with a broad host range.

Recombinant protein subunit COVID-19 vaccine-induced Guillain-Barré Syndrome in an adolescent: A case report.

Guillain-Barré Syndrome (GBS), an autoimmune neurological disease of peripheral nerves, has been causally associated with COVID-19 vaccination in adults. However, no such report has been published so far in children. We describe a 13-year-old female child who presented to the emergency department with complaints of bilateral upper limb, lower limb and truncal weakness over 3 days following first dose of recombinant protein subunit COVID-19 vaccine (Corbevax).

Limbic system symptoms of rabies infection.

Rabies is a fatal aggressive disease of the nervous system which predominantly causes motor and autonomic dysfunction. Limbic system involvement has been reported rarely, with limited data on its prevalence. The diagnosis becomes challenging when a patient presents with limbic system involvement in the absence of a clear history of an animal bite.

Exploring biotechnological and functional characteristics of probiotic yeasts: A review.

Probiotics are vital and beneficial organisms which offers the health benefits to the host organisms. The fungal probiotic field is one of the developing fields nowadays. Yeast has an enormous and diverse group of microorganisms that is attracting and expanding the attention from researchers and industries.

Bugs as drugs: neglected but a promising future therapeutic strategy in cancer.

Effective cancer treatment is an urgent need due to the rising incidence of cancer. One of the most promising future strategies in cancer treatment is using microorganisms as cancer indicators, prophylactic agents, immune activators, vaccines or vectors in antitumor therapy. The success of bacteria-mediated chemotherapy will be dependent on the balance of therapeutic benefit and the control of bacterial infection in the body.

Association of exopolysaccharide genes in biofilm developing antibiotic-resistant Pseudomonas aeruginosa from hospital wastewater.

The study aimed to examine the relationship between antibiotic resistance, biofilm formation and genes responsible for biofilm formation. Sixty-six Pseudomonas aeruginosa isolates were obtained from hospital wastewater and analyzed for their antibiotic resistance. Biofilm production among the isolates was tested by indirect quantification method crystal violet assay.