Total atrioventricular block as a cardiac manifestation in Weil's disease: a case report.

Background: Weil's disease is an infection caused by Leptospira bacteria. Leptospirosis may cause arrhythmias, such as atrial fibrillation and ST-T segment changes. We report a rare case of total atrioventricular block induced by leptospirosis.

Effectiveness and Tolerability of an Emollient "Plus" Compared to Urea 10% in Patients With Mild-to-Moderate Atopic Dermatitis.

Background: Atopic dermatitis (AD) poses a challenge due to its chronic inflammatory nature. Recent research highlights microbiome dysbiosis as a key contributor. Emollients "plus" are modern moisturizers containing bacterial lysate, improving skin barrier function and reducing Staphylococcus aureus colonization, thus mitigating AD symptoms.

Systematic review: characteristics of myocarditis followed by fixed drug eruption and dry eye syndrome in patients who have been vaccinated with monkeypox in children and adults.

Background: The Monkeypox Virus (MPOX) has caused a surge in viral infections, leading to the WHO recognizing it as a public health emergency of international concern. MPOX infection shares clinical similarities with smallpox but can cause complications like myocarditis, anorectal pain, ocular lesions, kidney damage, or soft tissue superinfection. The study aims to understand the characteristics of myocarditis, fixed drug eruption, and dry eye syndrome in Monkeypox patients.

Current biosensing strategies based on in vitro T7 RNA polymerase reaction.

Recently, a unique behavior of T7 RNA polymerase has expanded its functionality as a biosensing platform. Various biosensors utilizing T7 RNA polymerase, combined with fluorescent aptamers, electrochemical probes, or CRISPR/Cas systems, have been developed to detect analytes, including nucleic acids and non-nucleic acid target, with high specificity and low detection limits. Each approach demonstrates unique strengths, such as real-time monitoring and minimal interference, but also presents challenges in stability, cost, and reaction optimization.

Varicella challenges: A case of respiratory tract complications in an elderly patient.

Varicella, caused by the varicella-zoster virus (VZV), is rarely reported in the elderly but often complicates with pneumonia. In this case report, we present a case of varicella pneumonia in the elderly. A 60-year-old man presented to the emergency room with vesicles filled with clear fluid that had appeared all over the body for the past four days.

Toxicity assessment and bioimaging potential of carbon dots synthesized from banana peel in zebrafish model.

Zebrafish serve as a pivotal model for bioimaging and toxicity assessments; however, the toxicity of banana peel-derived carbon dots in zebrafish has not been previously reported. The aim of this study was to assess the toxicity of carbon dots derived from banana peel in zebrafish, focusing on two types prepared through hydrothermal and pyrolysis methods. Banana peels were synthesized using hydrothermal and pyrolysis techniques and then compared for characteristics, bioimaging ability, and toxicity in zebrafish as an animal model.

Potential of soybean-velvet bean combination tempe in improving cognitive function.

Velvet bean is a native Indonesian legume containing L-dopa, yet it remains underutilized. The aim of this study was to analyze the effects of different types of tempe (soybean, velvet bean, and their combination) on cognitive function, brain histology, dopamine levels, and serum β-amyloid in rats, as well as to identify the parameters most influencing cognitive function, including brain mass and volume, hippocampal neuron count, and dopamine and β-amyloid levels. An experimental study was conducted using a completely randomized design with one factor: the protein source of diet.

The Role of Moisturizer Containing Anti-inflammatory on Skin Hydration in Mild-Moderate Atopic Dermatitis Patients.

Atopic dermatitis (AD) is a chronic, inflammatory skin condition characterized by eczema lesions and dry, itchy skin. Recent guidelines for the management of AD emphasize the importance of using moisturizers in the management of AD. This study is a double-blind clinical trial to determine the effectiveness of moisturizers containing anti-inflammatory ingredients compared with moisturizers without anti-inflammatory ingredients for skin hydration in mild to moderate adult AD patients for 14 days at the Dermatology and Venereology Outpatient Clinic at Dr.

Bovine trichomoniasis: A hidden threat to reproductive efficiency.

Bovine trichomoniasis is a reproductive illness that affects cattle causing pyometra, early to mid-pregnancy miscarriages, and lower birth rates. is a flagellated protozoan which first discovered in France in 1888 and composts three phases during its lifecycle including trophozoite, cyst, and pseudocyst. In addition, several factors contributed to the prevalence of trichomoniasis and fall into three categories are management, cow, and bull-related factors.

Development of peptone-based serum-free media to support Vero CCL-81 cell proliferation and optimize SARS-CoV2 viral production.

Background: Developing an optimal media for Vero cell lines is crucial as it directly influences cell survival, proliferation, and virus production. The use of serum in cell culture raises safety concerns in biological production. The United States Food and Drug Administration (FDA) and the European Medicines Agency have implemented stricter regulations on the use of animal-derived components in commercial protein manufacturing to ensure patient safety.

Norovirus detection technologies: From conventional methods to innovative biosensors.

The norovirus (NoV), known for its high contagion rate, is the leading cause of acute gastroenteritis. The development of a NoV vaccine is hindered by significant antigenic variation, lack of suitable models, unknown vaccine protection duration, limited human challenge studies, complex performance patterns, and the absence of a reliable in vitro cultivation system, making prevention, early detection, and control the only effective measures to mitigate outbreaks. This review aims to discuss about several norovirus biosensor for point-of-care analysis.

The influence of sleep quality of pregnant women on the incidence of stunting in children: A literature review.

Lifestyle changes have significant impact on the pattern of sleep-in pregnant women. Irregular sleep patterns in pregnant women can lead to anaemia and disturbances in the formation of growth hormones, hence, causing interference in the progress and maturation of children, which includes increased potentials for stunted growth. This literature review aims to discuss the influence of the sleep quality of pregnant women on the incidence of stunting of newborns.

Assessment of brand awareness and marketing techniques of health services by users of primary health centres in Indonesia.

Community health centres are of great importance in the context of disease prevention and health promotion. Nevertheless, the number of individuals who utilise health centres for preventive care is significantly lower than those who seek treatment for existing illnesses. The objective of this study was to provide insights into innovative marketing strategies and brand awareness to enhance the utilisation of primary health services.

Porcine reproductive and respiratory syndrome developments: An in-depth review of recent findings.

The porcine reproductive and respiratory syndrome (PRRS) virus (PRRSV) belonging to the Arteriviridae family is the cause of PRRS disease. After being discovered for the first time in the United States in 1987, this illness quickly expanded to Canada. The disease was initially discovered in late 1990 in Germany, from where it quickly spread throughout Europe.

Identification of different blood concentration of domestic cat () with Leucomalachite Green and Takayama reagent.

Background: Cases of cruelty can occur in wild animal, livestock, and pet animal. Cruelty to cats choose to be the background of this research because many cases of cruelty to cats have not been reported although the cases are still high.

Aim: The aim of this research was to know how much dilution of cat blood can still be detected by Leucomalachite Green (LMG) and Takayama reagent.

Revolutionizing efficiency: The path to sustainable oilfield services in Indonesia's energy landscape - The case of Pertamina drilling services.

Purpose: This study explores strategic and technological approaches for sustainable oil production in Indonesia, focusing on policy frameworks, eco-innovation, and supply chain resilience to align with national and global standards. It also analyzes the organizational transition of Pertamina Drilling Service Indonesia (PDSI) to better navigate industry challenges with the outcome of a framework sustainable practices.

Design/methodology/approach: Utilizing Soft Systems Methodology (SSM) to analyze primary qualitative data, the research examines PDSI's adaptation to depict the current business environment and challenges both domestically and globally, addressing industry demands.

Investigate the efficiency of primary care facilities in emergency situations by application of geographical and demographic standards using GIS.

Background: This study applied geographical standards (coverage distance) and demographic standards to investigate the capabilities of primary healthcare facilities to cover the largest area of the study area and the service area that can be accessed. This study was conducted to find out the sufficient number of primary healthcare (PHC) centers required to provide healthcare services to the entire community.

Methods: Data was obtained by applying geographic information system (GIS) techniques to analyze primary care facilities using the demographic and geographic standards for primary care facilities.

The influence of nanochitosan-incorporated edible coating on the characteristics of Pangasius (Pangasius sp.) fillet.

Nanochitosan is known to have the potential to protect fish fillets, highly perishable products, as it can penetrate deep into the meat tissue and has high antibacterial activity. This study aimed to analyze the effect of nanochitosan incorporation to edible coating in inhibiting the degradation of Pangasius fillet quality during storage. The fillets were soaked with 2 % chitosan and nanochitosan concentrations (1 %, 2 %, and 3 %), stored for 15 days, and its quality was assessed periodically.

Pinpointing sources of pollution using citizen science and hyperlocal low-cost mobile source apportionment.

Currently, methodologies for the identification and apportionment of air pollution sources are not widely applied due to their high cost. We present a new approach, combining mobile measurements from multiple sensors collected from the daily walks of citizen scientists, in a high population density area of Birmingham, UK. The methodology successfully pinpoints the different sources affecting the local air quality in the area using only a handful of measurements.