[Perioperative smoking cessation (conventional smoking and e-cigarettes) in 2023. A narrative review of the literature].

Introduction: Tobacco addiction is the leading cause of preventable death. During the perioperative period, patients who smoke are at increased risk of systemic as well as surgical site complications.

State Of The Art: Surgery is an ideal time for change of lifestyle habits.

Effect of PEG Anchor and Serum on Lipid Nanoparticles: Development of a Nanoparticles Tracking Method.

Polyethylene glycol (PEG) is used in Lipid Nanoparticles (LNPs) formulations to confer stealth properties and is traditionally anchored in membranes by a lipid moiety whose length significantly impacts the LNPs fate in vivo. C18 acyl chains are efficiently anchored in the membrane, while shorter C14 lipids are quickly desorbed and replaced by a protein corona responsible for the completely different fate of LNPs. In this context, a method to predict the biological behavior of LNPs depending on the lipid-PEG dissociation was developed using the Nanoparticle Tracking Analysis (NTA) method in serum.

Influence of Different Measurements on the Ability of P-SAP and DES-OSA Scores to Detect Severe Obstructive Sleep Apnea.

Background: Severe obstructive sleep apnea (sOSA) represents a risk factor of postoperative complications. Perioperative sleep apnea prediction (P-SAP) and DES-obstructive sleep apnea (DES-OSA) (DES being the acronym for 2 of the participating investigators and OSA for obstructive sleep apnea) scores were validated in the detection of such patients. They include the measurement of neck circumference (NC) and distance between thyroid and chin (DTC).

Predictability of the duration of motor blockade induced by unique injection of intrathecal prilocaine - an observational study.

Prilocaine is widely used for spinal anesthesia. Its intermediate effect makes it a valuable choice for one-day surgery. The duration of the motor blockade (DMB) may have an impact on the length of stay.

Comparison of clinical scores in their ability to detect hypoxemic severe OSA patients.

Background: Severe obstructive sleep apnea (sOSA) and preoperative hypoxemia are risk factors of postoperative complications. Patients exhibiting the combination of both factors are probably at higher perioperative risk. Four scores (STOP-Bang, P-SAP, OSA50, and DES-OSA) are currently used to detect OSA patients preoperatively.

Risk factors for nocturnal hypoxemia in severe obstructive sleep apnea patients.

Background: Severe obstructive sleep apnea (sOSA) and oxygen desaturations are both risk factors for postoperative complications. In some but not all patients, sOSA is associated with frequent oxygen desaturation episodes during sleep. The aim of this retrospective study was to identify the risk factors for exhibiting oxygen desaturation in patients with sOSA.

Influence of premedication with alprazolam on the occurence of obstructive apneas. A prospective randomized double-blind study.

Postoperative development or worsening of obstructive sleep apnea is a potential complication of anesthesia. The objective of this study was to study the effects of a premedication with alprazolam on the occurrence of apneas during the immediate postoperative period. Fifty ASA 1 - 2 patients undergoing a colonoscopy were recruited.

Pre-Operative Ability of Clinical Scores to Predict Obstructive Sleep Apnea (OSA) Severity in Susceptible Surgical Patients.

Background: Severe obstructive sleep apnea (OSA) is an independent risk factor for perioperative complications. Clinical scores such as Snoring, Tiredness, Observed apnea, high blood Pressure, Body Mass Index (BMI) higher than 35 kg m, Age older than 50 years, Neck circumference larger than 40 cm, and male gender (STOP-Bang), perioperative sleep apnea prediction (P-SAP), and OSA50 have been proposed for detecting OSA. We recently proposed a new score based on morphological metrics only, the DES-OSA score.

Obstructive Sleep Apnea and Smoking as a Risk Factor for Venous Thromboembolism Events: Review of the Literature on the Common Pathophysiological Mechanisms.

Venous thromboembolism events (VTE) are a common and preventable cause of postoperative complications. Interestingly, smoking and obstructive sleep apnea syndrome (OSA) affecting a large part of our population (and especially obese patients) are two underestimated predisposing factors of VTE. Many coagulation disorders favoring thromboembolism have been identified in the case of OSA and smoking and are reviewed in this article.

Development and Validation of a Morphologic Obstructive Sleep Apnea Prediction Score: The DES-OSA Score.

Background: Obstructive sleep apnea (OSA) is a common and underdiagnosed entity that favors perioperative morbidity. Several anatomical characteristics predispose to OSA. We developed a new clinical score that would detect OSA based on the patient's morphologic characteristics only.

Preoperative adherence to continuous positive airway pressure among obstructive sleep apnea patients.

Background: Obstructive Sleep Apnea (OSA) increases the perioperative risk of complications. Chronic use of Continuous Positive Airway Pressure (CPAP) by patients decreases the importance of comorbidities caused by the OSA. However, many patients do not adhere to the treatment.

[Perioperative tobacco cessation: potential benefits and principles of management].

Thirty percent of surgical patients undergoing routine surgery are smokers, and smoking is an additional risk for these patients. During the perioperative period, smokers are more prone than non smokers to present either systemic complications interesting the cardiovascular and pulmonary functions or specific complications related to the surgical procedure, such as infections, wound problems and delayed osteosynthesis. Therefore, coming-off from smoking addiction is an obvious prerequisite in these patients.

[Perioperative tobacco cessation: a crucial period to overcome clinical inertia and poor compliance].

Smoking concerns 30% of the patients scheduled to anesthesia. Tobacco is one of the most important risk factors for postoperative complications. There are two classes of complications: those induced by the smoking habits on the cardiovascular and the respiratory systems, and those that predispose to other complications by direct interference with processes required for the success of surgery: healing and immune responses.