Stevioside mitigates metabolic dysregulation in offspring induced by maternal high-fat diet: the role of gut microbiota-driven thermogenesis.

Maternal obesity poses a significant threat to the metabolic profiles of offspring. Microorganisms acquired from the mother early in life critically affect the host's metabolic functions. Natural non-nutritive sweeteners, particularly stevioside (STV), play a crucial role in reducing obesity and affecting gut microbiota composition.

Effects of extrusion temperature on structure and physicochemical properties of proso millet starch.

Due to its thermal stability, and high viscosity, proso millet starch has limited practical applications. Extrusion can alter the functional properties of starch by pre-gelatinization, but the specific effects of extrusion temperature on starch behavior are not clear. In this study, proso millet starch was modified using extrusion at varying temperatures (70 °C, 90 °C, 110 °C), and its structure as well as physicochemical properties were evaluated.

Amino acid-mTOR pathway-associated transcription factor GATAβ4 regulates storage protein expression in Bombyx mori.

Storage proteins (SPs) are hexameric macromolecular protein, an important component of insect serum protein, which plays a variety of roles in insect metamorphosis and development. However, their regulatory mechanisms remain unclear. Our previous studies revealed that the expression of SPs is regulated by nutritional signals and identified FoxO as a negative regulator of SPs in the silkworm Bombyx mori (B.

Elasticity of trachea in the silkworm: A role of gene BmMuc91C.

Respiration is a vital process essential for organism survival, with most terrestrial insects relying on a sophisticated tubular tracheal network. In the current study, a gene with repetitive sequence was identified within the silkworm genome. Designated as BmMuc91C, it contains a dozen repeated motifs "PSSSYGAPX" and "GGYSSGGX" in its sequence.

GABA-Decorated Nanocarrier for Smart Delivery of Fludioxonil for Targeted Control of Banana Wilt Disease.

Developing a targeted nanopesticide to control the vascular disease of banana in agriculture is crucial to improve pesticide utilization. In this study, according to the degree of functionalization, three γ-aminobutyric acid (GABA)-decorated nanocarriers (PSI-GABA, PSI-GABA, and PSI-GABA) were constructed for smart delivery of nonsystemic fungicide in banana phloem tissues. Fludioxonil (Flu) was loaded in nanocarriers to form Flu@PSI-GABA nanoparticles with a core/shell structure for control of banana wilt disease.

Bacillus species are core microbiota of resistant maize cultivars that induce host metabolic defense against corn stalk rot.

Background: Microbes colonizing each compartment of terrestrial plants are indispensable for maintaining crop health. Although corn stalk rot (CSR) is a severe disease affecting maize (Zea mays) worldwide, the mechanisms underlying host-microbe interactions across vertical compartments in maize plants, which exhibit heterogeneous CSR-resistance, remain largely uncharacterized.

Results: Here, we investigated the microbial communities associated with CSR-resistant and CSR-susceptible maize cultivars using multi-omics analysis coupled with experimental verification.

Insights into the activation mechanism of Bm-CPA: Implications for insect molting regulation.

Carboxypeptidase A has been found across various animal species, yet its activation mechanism during the insect molting process remains elusive. Our study specifically delved into the activation mechanism of carboxypeptidase A (Bm-CPA), identified in Bombyx mori's molting fluid during metamorphosis. Initially, western blotting identified two forms of Bm-CPA, 65 kDa and 54 kDa, in the epidermis of silkworms during the molting stage.

Normal Reorientation for Scene Consistency.

With the remarkable progress of 3D scanning technique, the captured indoor scenes appear increasingly in last decade. Generating orientation-consistent normals for indoor point clouds is a fundamental and important task. The existing orientation rectification methods pay more attention to object-level targets with connected surface.

Chemical acylation of pea protein isolate hydrolysate with fatty acid N-hydroxysuccinimide esters: Effect on structure and functional properties.

Applications of pea protein in the food industry have been greatly restricted by its poor functional properties. In order to solve this problem, a novel technique combining enzymatic hydrolysis and fatty acid acylation has been applied in this work to construct a pea protein-fatty acid covalent complex that aims to improve its functional properties. The processed pea protein with increased water solubility tends to decrease the chance of self-aggregation.

Stevioside Ameliorates Prenatal Obesity Induced Postpartum Depression: The Potential Role of Gut Barrier Homeostasis.

Scope: Postpartum depression and cognitive impairment are the common complications of prenatal obesity. Stevioside is a non-nutritive natural sweetener with antioxidant and anti-inflammatory. However, its effects on depression behaviors and cognitive impairment induced by a high-fat diet (HFD) remain unclear.

Effect of Adding Fermented Proso Millet Bran Dietary Fiber on Micro-Structural, Physicochemical, and Digestive Properties of Gluten-Free Proso Millet-Based Dough and Cake.

The increasing demand for functional foods has pushed the food industry to produce fiber-enriched products. In this study, rheological, microstructural, physicochemical, and functional characteristics were investigated for whole proso millet dough and cake, fortified with fermented proso millet bran dietary fiber flour (F-DF). Results showed that proso millet flour is less absorbent and stable than the control group.

Whole Grain Proso Millet () Attenuates Hyperglycemia in Type 2 Diabetic Mice: Involvement of miRNA Profile.

This work aimed to investigate the hypoglycemic effects and underlying mechanism of whole grain proso millet (; WPM) on type 2 diabetes mellitus (T2DM). The results showed that WPM supplementation significantly reduced fasting blood glucose (FBG) and serum lipid levels in T2DM mice induced by a high-fat diet (HFD) combined with streptozotocin (STZ), with improved glucose tolerance, liver and kidney injury, and insulin resistance. In addition, WPM significantly inhibited the expression of gluconeogenesis-related genes , , , and .

supplementation ameliorates hyperuricemia modulating intestinal homeostasis and relieving inflammation.

Gut microbiota is associated with hyperuricemia progression and can be regulated by . However, the role of in hyperuricemia is still unknown. Thus, we constructed the mouse model of hyperuricemia using potassium oxonate and hypoxanthine treatment to explore the effects of supplementation on the development of hyperuricemia.

Genomic survey of NPF and NRT2 transporter gene families in five inbred maize lines and their responses to pathogens infection.

Besides manipulating nitrate uptake and allocation, nitrate transporters (NRTs) are also known to play crucial roles in pathogen defense and stress response. By blasting with the model NRT genes of poplar and Arabidopsis, a total of 408 gene members were identified from 5 maize inbred lines in which the number of NRTs ranged from 72 to 88. Phylogenetic analysis showed that the NRT genes of maize were classified into NRT1/PTR (NPF), NRT2 and NRT3 subfamilies, respectively.

The effect of ball milling on the structure, physicochemical and functional properties of insoluble dietary fiber from three grain bran.

The effects of ball milling processing on the structure, physicochemical, and functional properties of insoluble dietary fiber (IDF) in bran from prosomillet, wheat and rice were investigated. Meanwhile, the effect of IDF on glucose tolerance and blood lipid levels in mice was evaluated as well. With findings, for all three grains, the particle sizes of IDF were significantly reduced after ball milling treatment (p < 0.

Machine learning and experimental validation to construct a metastasis-related gene signature and ceRNA network for predicting osteosarcoma prognosis.

Objective: Osteosarcoma (OS) is more common in adolescents and significantly harmful, and the survival rate is considerably low, especially in patients with metastatic OS. The identification of effective biomarkers and associated regulatory mechanisms, which predict OS occurrence and development as well as improve prognostic accuracy, will help develop more refined protocols for OS treatment.

Methods: In this study, genes showing differential expression in metastatic and non-metastatic types of OS were identified, and the ones affecting OS prognosis were screened from among these.

Involvement of intestinal flora and miRNA into the mechanism of coarse grains improving type 2 diabetes: an overview.

The prevalence of type 2 diabetes has been growing at an increasing rate worldwide. Dietary therapy is probably the easiest and least expensive method to prevent and treat diabetes. Previous studies have reported that coarse grains have anti-diabetic effects.

The effect of chronic exposure to a low concentration of perfluorooctanoic acid on cognitive function and intestinal health of obese mice induced by a high-fat diet.

Perfluorooctanoic acid (PFOA) is a persistent organic pollutant associated with many adverse health risks. Evidence suggests that obese individuals may be more susceptible to environmental substances. In the present work, we explored the effects of PFOA exposure on the cognitive function and intestinal health of obese mice.

Point Cloud Completion Via Skeleton-Detail Transformer.

Point cloud shape completion plays a central role in diverse 3D vision and robotics applications. Early methods used to generate global shapes without local detail refinement. Current methods tend to leverage local features to preserve the observed geometric details.

Rank-PointRetrieval: Reranking Point Cloud Retrieval via a Visually Consistent Registration Evaluation.

Point cloud-based place recognition is a fundamental part of the localization task, and it can be achieved through a retrieval process. Reranking is a critical step in improving the retrieval accuracy, yet little effort has been devoted to reranking in point cloud retrieval. In this paper, we investigate the versatility of rigid registration in reranking the point cloud retrieval results.

Seamless Texture Optimization for RGB-D Reconstruction.

Restoring high-fidelity textures for 3D reconstructed models are an increasing demand in AR/VR, cultural heritage protection, entertainment, and other relevant fields. Due to geometric errors and camera pose drifting, existing texture mapping algorithms are either plagued by blurring and ghosting or suffer from undesirable visual seams. In this paper, we propose a novel tri-directional similarity texture synthesis method to eliminate the texture inconsistency in RGB-D 3D reconstruction and generate visually realistic texture mapping results.

Unsupervised Intrinsic Image Decomposition Using Internal Self-Similarity Cues.

Recent learning-based intrinsic image decomposition methods have achieved remarkable progress. However, they usually require massive ground truth intrinsic images for supervised learning, which limits their applicability on real-world images since obtaining ground truth intrinsic decomposition for natural images is very challenging. In this paper, we present an unsupervised framework that is able to learn the decomposition effectively from a single natural image by training solely with the image itself.

Neighbor Reweighted Local Centroid for Geometric Feature Identification.

Identifying geometric features from sampled surfaces is a significant and fundamental task. The existing curvature-based methods that can identify ridge and valley features are generally sensitive to noise. Without requiring high-order differential operators, most statistics-based methods sacrifice certain extents of the feature descriptive powers in exchange for robustness.

Targeted delivery of emamectin benzoate by functionalized polysuccinimide nanoparticles for the flowering cabbage and controlling Plutella xylostella.

Background: Plutella xylostella, one of the most destructive and cosmopolitan pests of cruciferous crops, is especially harmful to the young tissues of the flowering cabbage (Brassica campestris L.). Although emamectin benzoate (EB) has high insecticidal activity against P.

Chemical constituents with inhibition against TNF-α from Merrillanthus hainanensis.

Two new steroidal glycosides oxystauntoside A (1) and oxystauntoside B (2), together with sixteen known compounds (3-18) were isolated from the 95% ethanol extract of Merrillanthus hainanensis. Their structures were characterized by extensive spectroscopic analysis including NMR and mass spectra and single crystal X-ray crystallography. The absolute configuration of 1 and 2 were further determined by ECD calculations.