Publications by authors named "Chenxi Zhu"

Emerging contaminants (ECs) are characterized by their widespread environmental distribution and low concentrations, posing significant challenges for their effective removal from source wastewater. To better deal with the problems associated with ECs, we developed a robust Fe-Mn bimetallic catalyst supported on N-doped biochar (FM@NBC-8) for peroxymonosulfate (PMS)-mediated advanced oxidation system, in which bisphenol A (BPA) was investigated as a typical EC. Particularly, complete degradation of BPA in the FM@NBC-8/PMS system was achieved within 5 min, accompanying with a high TOC removal.

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Introduction: Rheumatoid arthritis (RA) is a prevalent autoimmune disease with synovial inflammation and hyperplasia, which can potentially cause degradation of articular cartilage, ultimately causing joint deformity, and impaired function. However, exact mechanisms underlying RA remain incompletely understood. This study seeks to uncover genomic signatures and potential biomarkers of RA, along with exploring the biological processes involved.

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Cold stress during overwintering is considered a bottleneck problem limiting the development of the red tilapia ( spp.) industry, and the regulation mechanism is currently not well understood. In this study, the fish (initial weight: 72.

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Anodic oxidation (AO) has been extensively hailed as a robust and promising technology for pollutant degradation, but the parasitic formation of oxychlorides (ClO) would induce a seriously over-evaluated electrochemical COD removal performance and dramatical biotoxicity increasement of the AO-treated Cl-laden effluents. Herein, we shed new light on the roles of HO high-efficiently electrogenerated in three-dimensional (3D) reactor in inhibiting ClO production and promoting pollutant degradation, which has been overlooked in previous literature. Total yield of ClO in phenol simulated wastewater containing 30 mM Cl was dropped from 25 mM and 24.

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  • This observational study examined the prevalence of diastasis recti abdominis (DRA) in men, identifying risk factors and potential adverse outcomes while exploring diagnostic criteria.
  • A total of 1,575 men participated, and the study revealed a DRA prevalence of 29.78% using an interrectus distance (IRD) > 2 cm, which decreased to 10.16% with an IRD > 3 cm.
  • Key influencing factors included age, BMI, smoking, and exercise, while no strong connections were found between DRA and abdominal muscle function or quality of life, although hernias were significant when using the > 3 cm criterion.
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Bovine parainfluenza virus type 3 (BPIV3) is a viral respiratory pathogen that infects cattle and causes significant economic losses. We generated a recombinant adenovirus called rHAd5-F + HN by expressing the fusion (F) and hemagglutinin-neuraminidase (HN) glycoprotein of BPIV3 using the human adenovirus serotype 5 (rHAd5). We evaluated its effects on humoral and cellular immune responses in mice (n = 45) and calves (n = 9).

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  • * Single-cell sequencing revealed distinct neutrophil populations in arthritis models, with one group showing high levels of neutrophil cytoplasmic factor 1 (NCF1) and a reactive oxygen species (ROS) response in primed mice, while this response decreased in boosted mice as arthritis developed.
  • * The study found that NCF1-deficient neutrophils showed increased inflammation and arthritis severity, linked to metabolic changes that shifted energy pathways, suggesting that understanding ROS regulation in neutrophils could lead to better RA prevention and treatment strategies.
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  • The study analyzed the prevalence of diastasis recti abdominis (DRA) among 1,000 postpartum women over 30 years, finding significant occurrence especially with an inter-recti distance (IRD) greater than 2 cm (36% at 3 years postpartum).
  • Key risk factors identified for DRA included higher body mass index (BMI), greater number of pregnancies, having twins, and diabetes, affecting different time points postpartum (e.g., BMI was significant at 10 years).
  • The results suggest a need to refine diagnostic criteria for DRA to minimize unnecessary diagnoses and improve early intervention strategies for affected women.
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Purpose: To propose a hybrid transverse gradient coil design method that leverages current density-based methods and nonuniform rational B-spline (NURBS) curves to optimize the performance and manufacturability of gradient coils.

Methods: Our method begins by generating an initial wire configuration using a density-based method. Then, we fit NURBS curves to the configuration, and adjust the control parameters of these curves to meet performance requirements.

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  • * Researchers created virus-like particles (VLPs) from BCoV by co-infecting cells with recombinant baculoviruses and tested these VLPs as a vaccine in mice and cattle, using adjuvants to enhance immune response.
  • * Results showed significant increases in antibody levels and immune cell activity in both mice and cattle after vaccination, indicating that BCoV VLPs could be a promising candidate for future vaccine development.
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Introduction And Hypothesis: The objective was to investigate whether diastasis recti abdominis (DRA) can cause adverse outcomes for different long-term postpartum women.

Methods: We recruited 437 long-term postpartum women at five different time points (3, 5, 10, 20, and 30 years postpartum respectively). Inter-recti distance (IRD) and linea alba or umbilical hernia were measured by ultrasound.

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Background: Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by multi-organ involvement and the presence of autoantibodies, pathogenic factors that can serve as diagnostic biomarkers. The current research has been focusing on exploring specific autoantigens with clinical relevance for SLE subtypes. In line with this objective, this study investigated potential antigenic targets associated with specific phenotypes in SLE by leveraging an omics-based approach combined with immunoassay techniques.

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The extensive use of plastic products has exacerbated micro/nanoplastic (MPs/NPs) pollution in the atmosphere, increasing the incidence of respiratory diseases and lung cancer. This study investigates the uptake and cytotoxicity mechanisms of polystyrene (PS) NPs in human lung epithelial cells. Transcriptional analysis revealed significant changes in cell adhesion pathways following PS-NPs exposure.

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The global prevalence and accumulation of plastic waste is leading to pollution levels that cause significant damage to ecosystems and ecological security. Exposure to two concentrations (1 and 5 mg/L) of 500 nm polystyrene (PS)-nanoplastics (NPs) for 14 d was evaluated in Simocephalus vetulus using transcriptome and 16 s rRNA sequencing analyses. PS-NP exposure resulted in stress-induced antioxidant defense, disturbed energy metabolism, and affected the FoxO signaling pathway, causing neurotoxicity.

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Doxorubicin (Dox) is extensively used as an antitumor agent, but its severe cardiotoxicity significantly limits its clinical use. Current treatments for Dox-induced cardiotoxicity are inadequate, necessitating alternative solutions. This study evaluated the effects of sarmentosin, a compound from Sedum sarmentosum, on Dox-induced cardiotoxicity and dysfunction.

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This study used berberine hydrochloride to treat the Asian paddle crab, Charybdis japonica infected with the Gram-negative bacterium Aeromonas hydrophila at concentrations of 0, 100, 200 and 300 mg/L. The effect of berberine hydrochloride on the survival rate and gut microbiota of C. japonica was investigated.

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Article Synopsis
  • Feline coronavirus (FCoV) is a major cause of death in cats, prompting the development of a vaccine using FCoV virus-like particles (VLPs) with specific proteins and adjuvants.
  • Results showed that mice and FCoV-negative cats produced high levels of specific antibodies after vaccination, indicating a strong immune response.
  • In FCoV-positive cats, booster shots led to reduced viral load in feces and negative conversion of the virus in some cases, suggesting the vaccine's potential effectiveness in preventing FCoV infection.
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Consuming a substantial quantum of energy (~165 TW h), the chlor-alkali industry garners considerable scholarly and industrial interest, with the anode reaction involving the oxidation of chloride ions being a paramount determinant of reaction rates. While the dimensionally stable anode (DSA) displays commendable catalytic activity and longevity, they rely on precious metals and exhibit a non-negligible side reaction in sodium hypochlorite (NaClO) production, underscoring the appeal of metal-free alternatives. However, the molecules and systems currently available are characterized by intricate complexity and are not amenable to large-scale production.

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A comprehensive bioinformatics analysis was conducted to elucidate the innate immune response of Charybdis japonica following exposure to Aeromonas hydrophila. This study integrated metabolomics, 16S rRNA sequencing, and enzymatic activity data to dissect the immune mechanisms activated in response to infection. Infection with A.

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Perfluorooctane sulfonate (PFOS) is a typical persistent organic pollutant that is characterized by environmental persistence, bioaccumulation, and toxicity. In this study, we investigated the gut microbial response of the red claw crayfish Cherax quadricarinatus after 28 days of exposure to 0 ng/L, 1 ng/L, 10 μg/L, or 10 mg/L of PFOS as a stressor. We measured oxidative stress-related enzyme activities and expression of molecules related to detoxification mechanisms to evaluate the toxic effects of PFOS.

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Conflict in peer and family relationships becomes more common in the adolescent period when compared to previous developmental periods. These typical developmental challenges can be exacerbated in the context of poor emotion regulation skills. Using daily diary data, the current study examined the stress spillover effects of peer and family stress on one another, as well as the moderating role of emotion regulation challenges (i.

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Background: Studies have shown that sphingomyelin (SM) and its metabolites play signaling roles in the regulation of human health. Endogenous SM is involved in metabolic syndrome (MetS), while dietary SM supplementation may maintain lipid metabolism and prevent or alleviate MetS. Therefore, we hypothesized that dietary SM supplementation is beneficial for human health.

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Cu-based liquid-like thermoelectric materials have garnered tremendous attention due to their inherent ultralow lattice thermal conductivity. However, their practical application is hampered by stability issues under a large current or temperature gradient. It has been reported that introduction of copper vacancies can enhance the chemical stability, whereas the micromechanism behind this macroscopic improvement still remains unknown.

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This study investigated the effects of nanoplastics (NPs) of varying particle sizes (75, 500, and 1000 nm) and concentrations (2.5 and 10 mg/L) on the gut health of Chiromantes dehaani. The experimental groups included a control (Cg0), and varying combinations of particle size and concentration.

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