Navigating the challenges: A case of iatrogenic cervical esophageal perforation following thyroid surgery.

Introduction: Iatrogenic cervical esophageal perforation (ICEP) represents a rare and challenging surgical complication that results in significant morbidity and mortality. This is a case report of a cervical esophageal fistula that resulted from an iatrogenic perforation following thyroid surgery, treated with surgical repair followed by negative pressure wound therapy (NPWT).

Presentation Of Case: A 43-year-old female was presented with an infected post-total thyroidectomy and bilateral radical neck dissection two weeks prior.

The core of patient-participation in the Intensive Care Unit: The patient's views.

Objectives: Patient participation is an established concept in public welfare. However, reports of the phenomenon of patient participation during intensive care from the patient's point of view are scarce. Therefore, the aim of this study was to explore the meaning of patient participation in the intensive care unit from the patient's perspective.

Metabolic Syndrome-Related Features in Controlled and Resistant Hypertensive Subjects.

Background: Metabolic syndrome (MetS) is widespread among hypertensive patients. Clinical features and potential biomarkers of MetS in the presence of hypertension and resistant hypertension (RHTN) represent a great area of interest for investigation.

Objective: The purpose of this study was to evaluate the prevalence of MetS and the clinical features associated with it in resistant and mild to moderate hypertensives.

Specific enzyme functionalities of Fusarium oxysporum compared to host plants.

The genus Fusarium contains some of the most studied and important species of plant pathogens that economically affect world agriculture and horticulture. Fusarium spp. are ubiquitous fungi widely distributed in soil, plants as well as in different organic substrates and are also considered as opportunistic human pathogens.

A Computational Methodology to Overcome the Challenges Associated With the Search for Specific Enzyme Targets to Develop Drugs Against .

We present an approach for detecting enzymes that are specific of compared with and provide targets that may assist research in drug development. This approach is based on traditional techniques of sequence homology comparison by similarity search and Markov modeling; it integrates the characterization of enzymatic functionality, secondary and tertiary protein structures, protein domain architecture, and metabolic environment. From 67 enzymes represented by 42 enzymatic activities classified by AnEnPi (Analogous Enzymes Pipeline) as specific for compared with , only 40 (23 Enzyme Commission [EC] numbers) could actually be considered as strictly specific of and 27 enzymes (19 EC numbers) were disregarded for having ambiguous homologies or analogies with .

Cost of the Diet (CoD) tool: first results from Indonesia and applications for policy discussion on food and nutrition security.

Background: The Minimum Cost of a Nutritious Diet (MCNut) is the cost of a theoretical diet satisfying all nutrient requirements of a family at the lowest possible cost, based on availability, price, and nutrient content of local foods. A comparison with household expenditure shows the proportion of households that would be able to afford a nutritious diet.

Objective: To explore using the Cost of Diet (CoD) tool for policy dialogue on food and nutrition security in Indonesia.

[Complete atrioventricular block in Kearns-Sayre syndrome].

A thirty-three year old woman, known to have Kearns-Sayre syndrome for eight years, had an ECG pattern of right bundle branch block and left anterior fascicular block that evolved to complete atrioventricular block, leading her to a syncopal episode. A temporary pacemaker and a permanent one were installed. The patient has been asymptomatic so far.