Risk factors for methicillin-resistant Staphylococcus aureus and extended-spectrum ß-lactamase producing Enterobacterales in patients with diabetic foot infections requiring hospital admission.

Objective: Methicillin-resistant Staphylococcus aureus (MRSA) and extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) may complicate the treatment of diabetic foot infections (DFIs). The aim of this study was to determine the risk factors for these pathogens in DFIs.

Methods: This was a prospective observational study of 167 consecutive adult patients with DFIs.

Critical overview of current anthropometric methods in comparison with a new index to make early detection of overweight in Spanish university students: the normalized weight-adjusted index.

Background: overweight and obesity have been increasing, and university students are an important target for prevention programs. Previous studies have reported differences in the diagnosis between different anthropometric methods, so some students can be misclassified depending on the method used.

Objective: to evaluate the efficacy of different anthropometric methods to detect those university students in a probable status of overweight, including a comparison with a new proposed method, the normalized weight-adjusted index (NWAI).

Impact of support networks for breastfeeding: A multicentre study.

Background: The rates of breastfeeding worldwide are slowly improving since 1996. Europe is still trailing behind the global breastfeeding incidence and prevalence rates. Thus, breastfeeding promotion, protection, prolongation and support have become an important challenge as breastfeeding sharply decreases in the first six months of life.

[Influence of initial protocolized treatment with steroids in length of stay and costs of community acquired pneumonia].

Objective: The aim of the study was to analyze the impact of steroid treatment in patients with community acquired pneumonia (CAP), both in length of stay and economical cost of admission at a clinical university hospital.

Methods: Prospective study of admitted patients with the diagnosis of CAP, both in Internal Medicine and Infectious diseases department. The study was conducted from January to march 2015; patients receiving steroids from diagnosis to end of antibiotic treatment were classified as group I; otherwise, they were considered in group II.

Acoustic radiation force impulse imaging for detection of liver fibrosis in overweight and obese children.

Background Acoustic radiation force impulse (ARFI) is a non-invasive alternative to a liver biopsy for the evaluation of liver fibrosis (LF). Purpose To investigate the potential usefulness of acoustic radiation force impulse ARFI for detecting LF in overweight and obese children Material and Methods A cross-sectional study was conducted in 148 schoolchildren. A diagnosis of non-alcoholic fatty liver disease (NAFLD) and LF was based on ultrasound (US) and ARFI shear wave velocity (SWV).

[Design and implementation of an outpatient parenteral antimicrobial therapy program in primary care: the experience at a second level hospital].

Objective: Outpatient parenteral antimicrobial therapy (OPAT) programs are a good assistance option in a wide variety of infectious diseases. Our aim was to design and implement an OPAT program in the area of influence of a second-level hospital, with no Home Hospitalization Service available, being necessary close collaboration between hospitalization and Primary Care teams, describe our cohort, analyse the antimicrobial treatment indicated and evaluate the prognostic and risk factors associated with readmission and mortality.

Methods: Prospective study cohorts of patients admitted to the OPAT programme, from 1 January 2012 to 31 May 2015.

Comparative study analysing women's childbirth satisfaction and obstetric outcomes across two different models of maternity care.

Objectives: To describe the differences in obstetrical results and women's childbirth satisfaction across 2 different models of maternity care (biomedical model and humanised birth).

Setting: 2 university hospitals in south-eastern Spain from April to October 2013.

Design: A correlational descriptive study.

Prospective randomized controlled study to assess the value of a hemostatic and sealing agent for preventing seroma after axillary lymphadenectomy.

Background And Objectives: Postoperative seroma after axillary lymphadenectomy leads to an increased use of resources and an impaired quality of life of patients. This randomized clinical trial was designed to assess the value of a hemostatic and sealing agent for decreasing seroma occurrence after axillary lymphadenectomy.

Methods: A prospective, randomized, blind study was conducted on 91 axillary lymphadenectomies distributed into a control group (n = 47) and a test group in which a collagen sponge coated with human coagulation factors was used (n = 44).

Episiotomy and its relationship to various clinical variables that influence its performance.

Objective: to understand the episiotomy rate and its relationship with various clinical variables.

Method: a descriptive, cross-sectional, analytic study of 12,093 births in a tertiary hospital.

Variables: Parity, gestational age, start of labor, use of epidural analgesia, oxytocin usage, position during fetal explusion, weight of neonate, and completion of birth.

The COL1A1 SP1 polymorphism is associated with lower bone mineral density in patients treated with valproic acid.

Objective: The aim of this study was to determine the possible relationship between the Sp1 polymorphism of gene COL1A1 and bone metabolism disorder in individuals with epilepsy.

Methods: To this end, we carried out an observational cross-sectional study on 64 patients in monotherapy with an antiepileptic drug. The patients were classified on the basis of the presence of the 's' allele of the COL1A1 Sp1 polymorphism.

Use of antibiotics at a University Clinic Hospital: effect of protocolized antibiotic treatment in the evolution of hospital patients with infections.

Objectives: To analyse factors associated to "failure" in patients under antibiotic (AB) treatment at a third level hospital.

Patients And Methods: All patients receiving an AB treatment along April 2012 were prospectively observed and factors associated to failure were analyzed. Failure was defined as clinical or microbiological failure, relapse or death.

Can Clinical Assessment of Locomotive Body Function Explain Gross Motor Environmental Performance in Cerebral Palsy?

Gross Motor Function Classification System has discriminative purposes but does not assess short-term therapy goals. Locomotion Stages (LS) classify postural body functions and independent activity components. Assessing the relation between Gross Motor Function Classification System level and Locomotion Stages will make us understand if clinical assessment can explain and predict motor environmental performance in cerebral palsy.

Use and influence of Delivery and Birth Plans in the humanizing delivery process.

Objectives: get to know, analyze and describe the current situation of the Delivery and Birth Plans in our context, comparing the delivery and birth process between women who presented a Delivery and Birth Plan and those who did not.

Method: quantitative and cross-sectional, observational, descriptive and comparative cohort study, carried out over two years. All women who gave birth during the study period were selected, including 9303 women in the study.

Toxicity of a dental adhesive compared with ionizing radiation and zoledronic acid.

Background: To determine the toxicity of aqueous dilutions of a universal self-priming dental adhesive (DA) and comparing these with those elicited by exposure to ionizing radiation (IR), Zoledronic acid (Z) treatment and the synergic effects of the combined treatment with IR+Z.

Material And Methods: The genotoxic effect of DA was determined by the increase in the frequency of micronuclei in cytokinesis-blocked in cultured human lymphocytes before and after exposure to 2Gy of X-rays. The cytotoxic effect was studied by using the MTT cell viability test in normal prostate cell lines (PNT2) after exposure to different X-ray doses (0Gy-20Gy).

[Development and validation of an instrument designed to measure the impact of networks of support for breastfeeding].

Background: the hypothesis of this study is that there are not enough validated questionnaires that measure the impact of networks to support breastfeeding for the Spanish speaking population.

Objective: For this reason, we ask as a general objective of this study, to develop and validate (in terms of content and construct) a quantitative instrument of measure.

Method: We evaluated the content validity, subjecting the survey to a breastfeeding expert's opinion in the Region of Murcia.

Reduction of HbA1c levels following nonsurgical treatment of periodontal disease in type 2 diabetics.

Objectives: A study was made of the effect of nonsurgical periodontal treatment upon blood glucose control in type 2 diabetics with periodontal disease.

Study Design: A pre-post repeated measures analytical design was used, with a PubMed search of the related articles published up until December 2008.

Results: The improvement in glycosylated hemoglobin (HbA1c) after nonsurgical periodontal treatment on comparing the baseline (8.

Galactography: an application of the Galactogram Imaging Classification System (GICS).

Background: Galactography is the technique of choice for investigating pathological nipple discharge. However, there is no standardized interpretation system for this procedure.

Purpose: To evaluate radiological and histological correlation using a Galactogram Imaging Classification System (GICS).

Urethrography in men: conventional technique versus clamp method.

Purpose: To compare examination adequacy and patient discomfort during retrograde urethrography (RUG) performed by using the conventional balloon method versus those of RUG and voiding cystourethrography (VCUG) performed with the clamp method of using drip infusion for the administration of contrast material.

Materials And Methods: This prospective study was approved by the institutional review board; written informed consent was obtained from all patients. Eighty men (mean age, 64.

[Immunohistochemical characterisation of breast cancer: towards a new clasification?].

Background: The aim of this paper is to determine the possible association between five different profiles of immunohistochemical expression related to clinical, histopathological and immunohistochemical known prognostic value variables for breast cancer.

Material And Method: A total of 194 breast carcinoma tumour samples were studied. In this study five groups or immunohistochemical profiles were defined, based on expression of hormone receptors (oestrogen or progesterone) and/or Her2/neu (luminal-type A, luminal-type B, mixed profile, Her2/neu profile and triple-negative-type profile) and we studied whether there are differences between them with regard to clinical, histopathological and immunohistochemical variables that have a known prognostic significance.

Effects of frequency of static stretching on straight-leg raise in elementary school children.

Aim: The aim of this study was to evaluate the efficacy of different frequencies of a stretching exercise program on lower extremity range of motion (ROM) in prepubertal schoolchildren.

Methods: A total of 62 children were divided into 3 groups (experimental groups: A, B; control group: C). Experimental group A performed hamstring stretches for 5 min during the Physical Education classes over a full school term (9 months), 2 sessions per week (31 weeks, 62 sessions of Physical Education).

[Technical features of interest in lymphatic basin localization in breast cancer sentinel lymph node biopsy].

Objectives: The sentinel node is defined as the node with the highest probability of being involved in the case of lymphatic spread from a tumor. Accurate identification and biopsy of this node can avoid unnecessary lymphadenectomies. The aim of this study was to determine if there are differences in the number of isolated sentinel lymph nodes in breast cancer according to whether a mixed technique (vital dye plus isotopic tracer) or radiotracer alone is used and if there are differences in the detection of more than one lymphatic basin and in the number of lymphatic nodes depending on the site of tracer injection.

[Anatomical location of the primary tumor as a variable to be considered in sentinel node biopsy of cutaneous melanoma].

Introduction: The anatomical location of cutaneous melanoma has been suggested to be an independent prognostic factor. The aim of the present study was to determine whether the location of the primary tumor influences sentinel node detection in cutaneous melanoma.

Patients And Method: Two hundred twelve patients with primary cutaneous melanoma (96 of the limbs, 89 of the trunk and 27 of the head or neck) who underwent sentinel lymph node biopsy were studied.

Treatment of metastatic melanoma B16F10 by the flavonoids tangeretin, rutin, and diosmin.

Melanoma is one of the most frequently metastasizing malignant neoplasias. This study examines an experimental model of pulmonary metastasis and the B16F10 cell subline, highly metastatic in the lung. Antimetastatic effects of the flavonoids tangeretin, rutin, and diosmin were analyzed, and at the same time an analysis of the metastatic activity of ethanol was performed, considered to be necessary because it is used as a vehicle for administering the flavonoids.

[Experimental model for treating pulmonary metastatic melanoma using grape-seed extract, red wine and ethanol].

Introduction: Melanoma is one of the neoplasias that most frequently metastasize, especially in the lung, where represents a challenge in oncology since current treatment is ineffective, and mortality is high.

Material And Methods: Swiss mice (n = 52) were inoculated with 0.5 x 106 B16F10 cell lines and, later, given an oral administration of grape-seed extract, red wine or ethanol.

[Clinical recurrence of multinodular goiter after surgery. A multivariate study on the risk factors].

Introduction: In multinodular goiter there is no consensus on which is the most adequate surgical technique, since although the techniques with partial resection show lower risk of complications they are associated with a higher risk of recurrences. The objective of this study is to define the risk factors for recurrence of multinodular goiters after surgery in a series with a mean postoperative follow-up higher than 12 years.

Patients And Method: 231 multinodular goiters with partial thyroid surgery are analyzed.