Publications by authors named "BaoQingHu"
Characterization of a novel toll-like receptor and activation NF-κB signal pathway in triangle sail mussel Hyriopsis cumingii.
Comp Biochem Physiol B Biochem Mol Biol
August 2021
Article Synopsis
- The study identified and characterized a new Toll-like receptor (HcTLRn) in the freshwater pearl mussel H. cumingii, which is crucial for detecting and defending against pathogens in innate immunity.
- HcTLRn consists of 3725 bp and encodes a protein with 718 amino acids featuring several functional domains that are important for its role in immune response.
- The receptor's expression increases in response to various microbial stimuli, and it influences the activation of important immune pathways, particularly the NF-κB signaling pathway, highlighting its significance in the mussel's immune system.