Publications by authors named "BERNARDIN"

Accurate luminance-based image generation is critical in physically based simulations, as even minor inaccuracies in radiative transfer calculations can introduce noise or artifacts, adversely affecting image quality. The radiative transfer simulator, SWEET, uses a backward Monte Carlo approach, and its performance is analyzed alongside other simulators to assess how Monte Carlo-induced biases vary with parameters like optical thickness and medium anisotropy. This work details the advancements made to SWEET since the previous publication, with a specific focus on a more comprehensive comparison with other simulators such as Mitsuba.

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  • Researchers explored how different bacterial communities affect the growth and nutrient content of the purple pitcher plant, filling a gap in understanding microbial interactions with plants.
  • They found that a community enriched in decomposition resulted in larger leaves and significantly increased biomass compared to control plants.
  • The study highlights potential mechanisms, like chitinase activity, which explain how these bacterial functions support the growth of carnivorous plants.
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Difpad-Onco (nursing screening of the frailty of elderly people, at home, with oncological disease) aims to facilitate and complement the identification of frailties in elderly cancer patients by private practice nurses in the patient's home. It consists of the G8 Oncodage, a Mini-Cog screening for cognitive impairment, a history of falls, and social frailty. It is aimed at all cancer patients aged 70 and over.

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The identification of a point mutation (p.Ser59Leu) in the CHCHD10 gene was the first genetic evidence that mitochondrial dysfunction can trigger motor neuron disease. Since then, we have shown that this mutation leads to the disorganization of the MItochondrial contact site and Cristae Organizing System (MICOS) complex that maintains the mitochondrial cristae structure.

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  • Social determinants of health (SDOH), like community race, income, and education, significantly affect outcomes in pediatric out-of-hospital cardiac arrest (POHCA).
  • Analysis of data from over 27,000 POHCAs revealed that communities with lower minority populations, higher wealth, and better education had notably better rates of bystander CPR, AED use, and return of spontaneous circulation (ROSC).
  • The findings highlight the opportunity for public health interventions aimed at reducing health disparities linked to community SDOH to improve POHCA outcomes.
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The failure of bonded composite materials is accompanied by specific failure modes. These are specifically Mode I, Mode II, Mode III, and their combination (so-called mixed mode). These modes depend on the direction and type of loading.

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Background: Epidemiological studies suggest that metformin reduces the risk of developing several types of cancer, including gliomas, and improves the overall survival in cancer patients. Nevertheless, while the effect of metformin on cancer cells has been extensively studied, its impact on other components of the tumour microenvironment, such as macrophages, is less understood.

Results: Metformin-treated mouse bone marrow cells differentiate into spindle-shaped macrophages exhibiting increased phagocytic activity and tumour cell cytotoxicity coupled with modulated expression of co-stimulatory molecules displaying reduced sensitivity to inflammatory cues compared with untreated cells.

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  • Almost all autistic youths have special interests (SIs), and new research indicates that these interests may differ between genders, although existing measures might not fully capture these differences.
  • Identifying these gender differences is crucial, as autistic girls' SIs can be overlooked due to their more socially oriented nature compared to boys, who often have interests in more "typically male" areas.
  • A study involving 1,921 caregivers reveals both similarities and specific gender differences in SIs, highlighting the importance of understanding these distinctions to better support autistic youth and their families.
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Nearly all autistic youth have special interests (SIs), which are associated with many benefits and challenges. Most research on SIs has focused on the subject matter of SIs, with less focus on understanding how youth engage in their SIs. We conducted a qualitative study using inductive content analysis (ICA) to examine: (1) The modalities youth use to engage in their SIs, (2) the degree to which such modalities are described by caregivers as adaptive or maladaptive, and (3) the extent to which the SIs themselves are described by caregivers positively or negatively.

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Unlabelled: Microbial communities perform various functions, many of which contribute to ecosystem-level nutrient cycling via decomposition. Factors influencing leaf detrital decomposition are well understood in terrestrial and aquatic ecosystems, but much less is known about arthropod detrital inputs. Here, we sought to infer how differences in arthropod detritus affect microbial-driven decomposition and community function in a carnivorous pitcher plant, .

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Introduction: Health professionals have an opportunity to assist patients who are experiencing many types of violence, including human trafficking; however, current approaches are often not person-centered. The Provide privacy, Educate, Ask, Respect and Respond (PEARR) Tool, a recognized screening tool in the U.S.

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The Clinical High Risk for psychosis (CHR) is a heterogeneous condition with multiple symptoms. CHR screening is challenging in routine care, as a wide variety of questionnaires exists. We propose to explore the extent to which these questionnaires differ or overlap in item content.

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Scope: Disruption of the one carbon metabolism during development, i.e., following a gestational vitamin B9 and B12 deficiencies, is involved in birth defects and brain development delay.

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Alzheimer's disease (AD) is a neurodegenerative disease with only late-stage detection; thus, diagnosis is made when it is no longer possible to treat the disease, only its symptoms. Consequently, this often leads to caregivers who are the patient's relatives, which adversely impacts the workforce along with severely diminishing the quality of life for all involved. It is, therefore, highly desirable to develop a fast, effective and reliable sensor to enable early-stage detection in an attempt to reverse disease progression.

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Driving ability has been shown to be dependent on perceptual-cognitive abilities such as visual attention and speed of processing. There is mixed evidence suggesting that training these abilities may improve aspects of driving performance. This preliminary study investigated the feasibility of training three-dimensional multiple object tracking (3D-MOT)-a dynamic, speeded tracking task soliciting selective, sustained and divided attention as well as speed of processing-to improve measures of simulated driving performance in older and younger adults.

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We advanced a novel model to calculate viscoelastic lung compliance and airflow resistance in presence of mucus, accounting for the quasi-linear viscoelastic stress-strain response of the parenchyma (alveoli) tissue. We adapted a continuum-based numerical modeling approach for the lung, integrating the fluid mechanics of the airflow within individual generations of the bronchi and alveoli. The model accounts for elasticity of the deformable bronchioles, resistance to airflow due to the presence of mucus within the bronchioles, and subsequent mucus flow.

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Background: Electrophysiological impairments in the magnocellular visual system have been reported among patients with schizophrenia, but previous theories proposed that these deficits may begin in the retina. We therefore sought to evaluate the potential contribution of the retina by comparing retinal and cortical visual electrophysiological impairments between patients with schizophrenia and healthy controls.

Methods: We recruited patients with schizophrenia and age- and sex-matched healthy controls.

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  • Cancer cells increase their nucleotide supply by enhancing one-carbon metabolism, particularly through enzymes MTHFD1 and MTHFD2, which are targeted by the inhibitor TH9619.
  • TH9619 selectively kills cancer cells by inhibiting MTHFD1 and targeting nuclear MTHFD2, leading to the accumulation of 10-formyl-tetrahydrofolate and subsequent cell death due to thymidylate depletion.
  • This inhibition mechanism creates a 'folate trap' that is intensified by natural hypoxanthine levels, providing a new strategy for cancer treatment while also offering insights into one-carbon metabolic regulation.
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Blood analysis is one of the foundations of clinical diagnostics. In recent years, the analysis of proteins in blood samples by mass spectrometry has taken a jump forward in terms of sensitivity and the number of identified proteins. The recent development of parallel reaction monitoring with parallel accumulation and serial fragmentation (prm-PASEF) combines ion mobility as an additional separation dimension.

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Objectives: To describe endoscopic findings, foreign body location, success rate of removal and complications in dogs with bronchial vegetal foreign bodies.

Materials And Methods: The current study retrospectively evaluated the case records of dogs diagnosed with bronchial vegetal foreign bodies at a veterinary hospital centre between January 2010 and April 2020. Information retrieved included breed, sex, age, bodyweight, the season of presentation, presentation and duration of clinical signs, previous removal attempts performed by the referring veterinarian, foreign body location and endoscopic and imaging findings.

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Improving the reliability of automotive perceptive sensors in degraded weather conditions, including fog, is an important issue for road safety and the development of automated driving. Cerema has designed the PAVIN platform reproducing fog and rain conditions to evaluate optical automotive sensor performance under these conditions. In order to increase the variety of scenarios and technologies under test, the use of digital simulation becomes a major asset.

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