Purpose: The Adolescent Brain Cognitive Development (ABCD) Study is the largest longitudinal study on brain development and adolescent health in the United States. The study includes a sociodemographically diverse cohort of nearly 12,000 youth born 2005-2009, with an open science model of making data rapidly available to the scientific community. The ABCD Study® data has been used in over 1100 peer-reviewed publications since its first data release in 2018.
View Article and Find Full Text PDFAdolescent substance use is common with 11% to 31% of adolescents in 8th through 12th grade reporting illicit substance use. Of particular concern is the increasing rate of overdose deaths among adolescents. The likelihood of developing a substance use disorder (SUD) is linearly associated with frequency of use and inversely associated with age, such that young people with early onset of use are the most susceptible for later dependence.
View Article and Find Full Text PDFBackground: Chronic social defeat stress is a widely used depression model in male mice. Several proposed adaptations extend this model to females with variable, often marginal effects. We examine if the widely used male-defined metrics of stress are suboptimal in females witnessing defeat.
View Article and Find Full Text PDFBackground: Mycosis fungoides (MF) is the most common form of cutaneous T cell lymphoma. While multiple guidelines provide treatment recommendations, there are currently no clear treatment algorithms for MF. Chlormethine gel is recommended by major treatment guidelines as a first-line option for stage IA-IIA disease, and, on the basis of these guidelines, used in combination with other therapies in patients with advanced-stage MF in clinical practice.
View Article and Find Full Text PDFPsychol Sport Exerc
January 2025
This study aimed to identify attentional foci and coping strategies of elite fencers during competitive matches, explore the co-occurrences between both, and examine their impact on performance. Twenty-two epeeists (11 males and 11 females) from a national team took part in self-confrontation interviews during two simulated tournaments. Data were analysed using inductive and deductive content analyses.
View Article and Find Full Text PDFIn our inaugural year as , we are proud to support the dissemination of some of the highest quality research being conducted in our field. Choosing the "best" among stars is a tall order and most certainly misses the many ways articles make an impact: is the "best" the most interesting, most surprising, most educational, most important, most provocative, or most enjoyable? How to decide? This time around, we made some picks based on those that were methodologically rigorous and clinically salient. It is our pleasure to give a special "hats off" to the 2023 articles that we think deserve your attention or at least a second read!
View Article and Find Full Text PDFA critical piece in the launch of is the establishment of a high-quality and robust peer review process for incoming submissions. Indeed, peer review is the backbone of our scientific process. Here, we will discuss the importance of peer review, describe the process as we are expanding the journal family, and explain why and how you can be involved in the peer review process.
View Article and Find Full Text PDFJ Am Acad Child Adolesc Psychiatry
December 2024
Learning to predict threat is essential, but equally important-yet often overlooked-is learning about the absence of threat. Here, by recording neural activity in two nucleus accumbens (NAc) glutamatergic afferents during aversive and neutral cues, we reveal sex-biased encoding of threat cue discrimination. In male mice, NAc afferents from the ventral hippocampus are preferentially activated by threat cues.
View Article and Find Full Text PDFWeight variations are common in sporting life, with important inter-individual variability in the degree of an athlete's habitual weight loss. As a part of the WAVE study (NCT04107545), the main objective of this preliminary study was to determine whether the habitual degree of weight loss was associated with anthropometric, body composition, nutritional or psychometric profiles during a period of weight maintenance in athletes accustomed to weight variations. We hypothesized that athletes accustomed to a higher habitual degree of weight loss may have a higher body weight and body fat mass, and may present a more controlled diet regimen and cognitive restriction than athletes with a lower habitual degree of weight loss.
View Article and Find Full Text PDFJ Am Acad Child Adolesc Psychiatry
August 2024
Discrimination and structural factors that promote discrimination and sociocultural inequities are social determinants of health that contribute to poorer health outcomes among minoritized youth. Discrimination consists of institutional or individual-level biases leading to disparate and unequitable access to resources. If individuals are aware of these experiences and their impact on one's own ability to access resources or opportunities, individuals may self-report these occurrences.
View Article and Find Full Text PDFBackground: There is a critical global shortage of nurses in mental health, with workforce attrition due in large part to workplace stressors. Proactive strengths-based interventions to strengthen nurses' capacity to manage stress and improve mental health, wellbeing and resilience may also support workforce retention.
Objective: To determine the effects of a resilience-building programme on mental health nurses' coping self-efficacy (primary outcome), and psychological distress, wellbeing, resilience, posttraumatic growth, emotional intelligence behaviours, workplace belonging, and turnover intention (secondary outcomes).
Youth screen media activity is a growing concern, though few studies include objective usage data. Through the longitudinal, U.S.
View Article and Find Full Text PDFBackground: Stroke affects long-term physical and cognitive function; many survivors report unmet health needs, such as pain or depression. A hospital-led follow-up service designed to address ongoing health problems may avoid unplanned readmissions and improve quality of life.
Methods: This paper outlines the protocol for a registry-based, randomised controlled trial with allocation concealment of participants and outcome assessors.
Psoriasis is an inflammatory skin disease characterized by epidermal and immune dysfunctions. Although efficient, current topical treatments display adverse effects, including skin atrophy and burning sensation, leading to poor patient adherence. To overcome these downsides, pickering emulsions were formulated in which the calcitriol-containing dispersed phase was stabilized with either cyclosporin A- or tacrolimus-loaded poly(lactic-co-glycolic) acid nanoparticles.
View Article and Find Full Text PDFAtom probe tomography (APT) has been utilized to investigate the microstructure of two model borosilicate glasses designed to understand the solubility limits of phosphorous pentoxide (P2O5). This component is found in certain high-level radioactive defence wastes destined for vitrification, where phase separation can potentially lead to a number of issues relating to the processing of the glass and its long-term chemical and structural stability. The development of suitable focused ion beam (FIB)-preparation routes and APT analysis conditions were initially determined for the model glasses, before examining their detailed microstructures.
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