Publications by authors named "Athmika"
Genomic potential for exopolysaccharide production and differential polysaccharide degradation in closely related Alteromonas sp. PRIM-21 and Alteromonas fortis 1.
Antonie Van Leeuwenhoek
January 2023
Article Synopsis
- * This study focuses on the draft genome of an algae-associated strain, Alteromonas sp. PRIM-21, from India, revealing its similarities to the closely related strain A. fortis 1, including a high degree of genetic similarity and the presence of genes for EPS production.
- * The strain PRIM-21 possesses unique enzymes for degrading various polysaccharides, which may help it extract nutrients from its algal host, highlighting genetic differences in polysaccharide utilization among closely related Alter
Natural biopolymers have gained remarkable attention for bioremediation particularly in heavy metal removal and oil degradation due to their non-toxic nature and lack of secondary pollution. The exopolysaccharides (EPS) produced by the bacteria have become an important class of biopolymers that are employed in bioremediation. The bacteria isolated from the rhizospheric soil have higher metal tolerance and their EPS are effective in biosorption of heavy metals.
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- Halomonas malpeensis strain YU-PRIM-29 is a halophilic bacterium identified for its yellow pigment and ability to produce exopolysaccharides (EPS), which are important for various industrial applications.* -
- Whole genome sequencing revealed a total of 3,607,821 base pairs with genes related to EPS and capsular polysaccharide biosynthesis, showing that the EPS production is influenced by the carbon source used in cultures.* -
- Further analysis identified metabolites such as zeaxanthin, which has antioxidant properties, confirming the strain's potential for producing valuable industrial biomolecules.*
Development of drug resistance in opportunistic pathogens is one of the major healthcare challenges associated with infection management. Combination therapy has many advantages due to the simultaneous action of two drugs on two separate cellular targets. However, selection of the drugs should offer safety and synergistic interaction against most of the strains.
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- Uropathogenic bacteria contribute to urinary tract infections and kidney stone disease, with a specific strain (YU22) isolated from a struvite stone patient showing potential links to this condition.
- The strain YU22, sharing similarities with bacteria found on the International Space Station, exhibits virulence factors that facilitate colonization and infection, including motility and biofilm formation.
- Experimental results indicate that YU22 can thrive in the urinary environment, enhance struvite crystallization, and warrants further investigation to understand its health risks more comprehensively.