Genomic Surveillance of COVID-19 Variants With Language Models and Machine Learning.

The global efforts to control COVID-19 are threatened by the rapid emergence of novel SARS-CoV-2 variants that may display undesirable characteristics such as immune escape, increased transmissibility or pathogenicity. Early prediction for emergence of new strains with these features is critical for pandemic preparedness. We present , a supervised and causally predictive model using unsupervised latent space features of SARS-CoV-2 genome sequences.

Assessment of pediatric asthma exacerbation with the use of new PROMIS measures.

Objective: Patient reported outcome measures, such as the Patient Reported Outcomes Measurement Information System (PROMIS) may be used to assess patient functioning for asthma and aid in understanding the impact of asthma exacerbation. These domains may be utilized as endpoints in clinical trials and to guide clinical care. The purpose of this study was to determine psychometric properties of the new PROMIS measures for children with asthma, at baseline and with exacerbation.

Analysis of bone mineral density and content in children with molar incisor hypomineralization using dual-energy X-ray absorptiometry scan: A pilot study.

Aim: The objective was to evaluate the bone mineral density (BMD) and bone mineral content (BMC) in children affected with molar incisor hypomineralization (MIH) using dual-energy X-ray absorptiometry (DEXA) scan.

Materials And Methods: The study comprised a total of 30 children aged 6-10 years. Fifteen children were affected with MIH (moderate and severe variety) diagnosed using the European Academy of Paediatric Dentistry 2003 criteria, and remaining 15 children not affected with MIH serve as a control group.

Arrested root growth and concomitant failure of eruption of a developing tooth following open reduction and internal fixation of a pediatric mandibular fracture.

Mandible is one of the commonly fractured bone in children during maxillofacial trauma. These factures are usually managed conservatively but sometimes require open reduction and internal fixation (ORIF). Management of mandibular fracture in children is influenced by the presence of developing permanent tooth buds, minimal anchorage from primary teeth and facial growth and development.

Zirconia crowns for rehabilitation of decayed primary incisors: an esthetic alternative.

Esthetic management of extensively decayed primary maxillary anterior teeth requiring full coronal coverage restoration is usually challenging to the pediatric dentists especially in very young children. Many esthetic options have been tried over the years each having its own advantages, disadvantages and associated technical, functional or esthetic limitations. Zirconia crowns have provided a treatment alternative to address the esthetic concerns and ease of placement of extra-coronal restorations on primary anterior teeth.

Study of bone mineral density in patients with ankylosing spondylitis.

Introduction: Ankylosing spondylitis (AS) is an inflammatory rheumatic disease characterized by spine and sacroiliac joint involvement that mainly affects young male subjects. Bone Mineral Density (BMD) loss occurs in AS disease course. Bone loss in AS appears to be multifactorial and perhaps involves different mechanisms at different stages of disease.

Early medical abortion: a new regimen up to 49 days' gestation.

Aim: To evaluate a new regimen of mifepristone and misoprostol in early medical abortion up to 49 days of amenorrhoea.

Methods: One hundred healthy women requesting pregnancy termination up to 49 days gestation received 200 mg mifepristone followed by 800 microg misoprostol orally 24 h later. Statistical analysis was carried out by unpaired t-test.

Prevalence of malocclusion and abnormal oral habits in North Indian rural children.

This epidemiological investigation was conducted on a sample of 3164 rural children aged 6-15 years in Raipur Rani and Naraingarh blocks in the district of Ambala in Haryana. 29. 2 percent of rural children were found to have malocclusion whereas 70.