Publications by authors named "Anusha"

To determine the level of disability in patients suffering from tinnitus using the Tinnitus Handicap Inventory (THI) score, to evaluate the changes in otoacoustic emissions in a patient with tinnitus and evaluate the co-relation of the Tinnitus Handicap Inventory score with the Otoacoustic emission result This is an observational study done over a period of 6 months, in which patients aged more than 18 years who presented to the ENT OPD of our institute with complaints of tinnitus were considered for inclusion in the study. Patients with primary tinnitus, who consented to be part of the study were assessed for handicap caused by tinnitus using the Tinnitus Handicap Inventory (THI) score. All patients were subjected to Pure Tone Audiometry (PTA) and Screening OAE to look for the "Pass" or "Refer" in the OAE result.

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Background: The role of skin tone in determining tooth shade preferences is crucial in aesthetic dentistry. This study aims to evaluate the impact of skin tone on tooth shade selection by comparing preferences between dental professionals and laypersons.

Methods: A cross-sectional study was conducted with 100 participants, including 50 dental specialists (prosthodontists and endodontists) and 50 laypersons (teachers, engineers, and business owners).

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Background: Oral health is greatly impacted by visual impairment, which raises the possibility of dental treatment anxiety. Therefore, the goal of this research is to assess dental anxiety in children who are blind.

Aim And Objectives Of The Study: The intention of the study was to raise awareness of oral health among visually impaired children and to use the RMS-tactile scale (TS) to measure their anxiety levels.

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Background: Smokeless tobacco (SLT) use is a major public health problem in many parts of the world, including India. Despite this, smokeless tobacco often doesn't receive enough attention. The aim of this study was to assess the pH, moisture, nicotine levels, and warning labels on smokeless tobacco products sold in Pondicherry, India.

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This study describes the biosynthesis of nickel nanoparticles (Ni NPs) using gram-negative bacterium, Enterobacter cloacae. The synthesized Ni NPs were annealed at 350 °C for 3 h and characterized using various techniques. Powder X-ray diffraction analysis revealed the formation of Ni NPs with an average crystallite size of 48.

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Unravelling the intricate patterns of site-specific protein phosphorylation during Epimorphic regeneration holds the key to unlocking the secrets of tissue complexity. Understanding these precise modifications and their impact on protein function could shed light on the remarkable regenerative capacity of tissues, with potential implications for therapeutic interventions. In this study we have systematically mapped the global phosphorylation modifications within regenerating tissue of zebrafish caudal fins, elucidating the intricate landscape of signalling pathway associate with the regeneration process.

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Background: Thyroid auto-antibodies could be one of the many causes of infertility in women, especially with polycystic ovarian syndrome (PCOS) with a prevalence of 5%-15%. Patients with anti-thyroid antibodies have shown significantly lower fertilisation rates, implantation rates, lower pregnancy rates and increased risk of first-trimester abortions when compared with those without anti-thyroid antibodies.

Aim: The aim of the study was to assess the prevalence of thyroid auto-antibodies in euthyroid infertile women with PCOS and to compare the prevalence of thyroid autoantibodies in euthyroid infertile women with PCOS and without PCOS.

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Ectopic thyroid is a rare congenital anomaly that results from failure of decent from the foramen cecum to the primitive thyroid during the stage of embryogenesis. The specific prevalence ranges from 1 in 100,000-300,000 population. Development, genetics, and mutation play a role in the formation of ectopic thyroid.

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The production of enantiomerically pure compounds remains a vital and valuable objective in modern organic chemistry due to their broad applications in fields such as biosensing, optics, electronics, photonics, catalysis, nanotechnology, and drug or DNA delivery. Optically pure α-hydroxy ketones, in particular, are key structural components in many drugs and natural products with significant biological activity. Among these, benzoin type α-hydroxy ketones, which possess two adjacent functional groups, a carbonyl and a hydroxy group, are especially important.

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Article Synopsis
  • Cervical cancer is the fourth most common cancer in women worldwide, with around 600,000 new cases and 340,000 deaths each year.
  • Early-stage cervical cancer can be treated effectively, but options for metastatic cases are limited, highlighting the need for better diagnostic methods.
  • This paper reviews cervical cancer biomarkers and the use of electrochemical biosensors for detection, which offer improved sensitivity, cost-effectiveness, and simplicity in analysis compared to traditional methods.
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Stroke is a serious condition often resulting in mortality or long-term disability, causing cognitive, memory, and motor impairments. A reduction in cerebral blood flow below critical levels defines the ischemic core and penumbra: the core undergoes irreversible damage, while the penumbra remains viable but functionally impaired. This functional impairment activates complex cell signaling pathways that determine cell survival or death, making the penumbra a key target for therapeutic interventions to prevent further damage.

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Background: Oral health plays a critical role in overall well-being, particularly among adolescents, including those with intellectual disabilities. Caregivers, particularly mothers, play an essential role in guiding and supporting these adolescents in maintaining good oral health. This study examined the oral health problems and challenges faced by children with intellectual disabilities from the perspective of their mothers.

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  • Inducing spawning in female catfish is well understood, but stimulating male spermiation and understanding testicular maturation remains challenging, sparking research into gene profile changes during this process.
  • The study focused on creating de novo transcriptome assemblies for the Asian catfish (Clarias batrachus) and African catfish (C. gariepinus) to identify genes involved in male reproductive processes, particularly after administering human chorionic gonadotropin (hCG) during their reproductive phase.
  • Key findings showed an increase in steroidogenesis-related gene expressions (like star, cyp11b1, cyp17a, and cyp21a) after hCG treatment, along with unique reproduction-related genes differing between the species,
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Tuberculosis (TB) remains a significant global health challenge, necessitating strict adherence to medication for successful treatment and prevention of drug resistance. Adherence to a regular medication regimen is crucial in TB management, yet achieving high adherence rates among patients proves challenging due to various factors including forgetfulness, complexity of treatment schedules, and socioeconomic barriers. This study explores the potential of an automatic medicine dispenser (AMD) anchored system to improve medication adherence among TB patients and evaluates its impact through monitoring and feedback mechanisms.

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Aging is an irreversible and continuous biological process involving intricate and interconnected mechanisms. The present work is focused on unravelling the anti-aging mechanisms of mealworm protein and protein-enriched fruit bar and vegetable soup in D-galactose-induced aged mice. Mealworm protein and enriched products significantly enhanced body weight, organ indices, and gut health.

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  • Atrial fibrillation (AF) is a common heart rhythm disorder in the U.S. that affects millions, and it can lead to serious complications like rapid ventricular response (RVR).
  • An umbrella review of existing systematic reviews found IV diltiazem was more effective than IV metoprolol for controlling heart rate and reducing ventricular rates in patients experiencing AF with RVR.
  • However, the use of IV diltiazem was also associated with a higher risk of hypotension, indicating the need for further research to evaluate the balance between efficacy and safety for these treatments.
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  • * The study focused on identifying iron uptake proteins associated with the fungus and screened a library of over 15,000 compounds to find potential inhibitors that could disrupt fungal growth.
  • * Six promising small molecules were found to have low toxicity and strong binding capabilities to these proteins, which could lead to the development of effective antifungal treatments against mucormycosis.
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Self-assembly of biomolecules provides a powerful tool for a wide range of applications in nanomedicine, biosensing and imaging, vaccines, computation, nanophotonics, etc. The key is to rationally design building blocks and the intermolecule interactions. Along this line, structural DNA nanotechnology has rapidly developed by limiting DNA secondary structures to primarily well-established, B-form DNA duplexes, which can be readily and reliably predicted.

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Background: A major objective in the management of deep carious lesions involving proximal surfaces of primary molars is to control marginal leakage. This could occur due to dimensional changes or failure in the adaptation of pulp capping materials to the prepared cavity. Evaluation of microleakage is important for assessing the success of newer pulp capping materials.

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Aim: Socially handicapped children face a number of challenges including limited access to basic health including oral healthcare. The aim of this study is to determine the oral health status and treatment needs of socially handicapped children and to assess the effectiveness of the Comprehensive Dental Health Program (CDHP) on their oral health-related quality of life (OHRQoL).

Materials And Methods: A total of 97 children in the age-group of 7-14 years were enrolled in the study.

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  • Stiff-person syndrome (SPS) is a rare disorder that makes your muscles really stiff and causes problems with movement, especially in the trunk and close muscles.
  • There are different types of SPS, like classic SPS with widespread stiffness and partial SPS which affects just some limbs.
  • A young man showed signs of SPS with a forward-leaning posture and involuntary movements, and doctors used tests like MRI and blood work to confirm the diagnosis and treat him.
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Background: Dental Unit Water Line (DUWL) deliver water to different handpieces in a dental unit. The water in DUWL circulates in a closed system, where it is taken from a container. The quality of dental water is of considerable importance since patients and dental staff are regularly exposed to water and aerosols generated from dental equipment.

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