Publications by authors named "Anda"

Background: The Georgian Birth Registry (GBR) is a comprehensive digital birth registry covering 99.8% of births nationwide. By law, registration in the GBR is mandatory, with data primarily transferred from medical records (MRs) by designated personnel at medical facilities.

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Motion is vital for life. Currently, the clinical assessment of motion abnormalities is largely qualitative. We previously developed methods to quantitatively assess motion using visual detection systems (around-body) and stretchable electronic sensors (on-body).

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Anaerobic digestate animal effluent (ADAE) contains high N and P nutrients which need to be treated. In this study, an integrated process was proposed using a microalgae consortium of Chlorella and Scenedesmus. The system was designed for 71 m/d (medium-sized) and 355 m/d (large-sized) animals of ADAE.

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  • The study investigates the potential of using rice straw, along with protein extracted from leaves, as livestock feed to improve nutrition and digestibility.
  • Distilled water was found to be more effective than chemical solvents like 0.1 N NaOH for extracting protein from leaves, yielding higher protein and amino acid content.
  • Incorporating this distilled water-extracted protein into low-quality rice straw diets resulted in better fermentation and digestibility, suggesting a viable method to enhance livestock nutrition.
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  • The update of the Mexican Guidelines for the Treatment of Systemic Lupus Erythematosus has been developed with input from various experts across the country.
  • The new guidelines follow the GRADE system, which helps in evaluating the quality of evidence for healthcare recommendations.
  • Key new topics included in the update are vaccines, pregnancy, and cardiovascular risk, which were not addressed in the previous guidelines from 2017.
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Background: In response to substantial lead exposure, the autonomous republic of Adjara in Georgia initiated complementary blood lead level (BLL) testing for pregnant women as part of their antenatal care services in 2020.

Objectives: To study the background BLLs in pregnant and breastfeeding women in Adjara and explore the time-trends of BLLs from September 2020 to July 2023.

Methods: We used data on BLLs during pregnancy or postpartum from the lead screening program in Adjara, combined with data from the Georgian Birth Registry, totaling 9,510 women.

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  • Asgard archaea, key ancestors of Eukaryotes, have mobile genetic elements (MGEs) that are not well understood, and this study investigates two complete genomes from the Atabeyarchaeia lineage to explore these elements.
  • The research identifies 18 MGEs in Atabeyarchaeia, including a notable 20.67 kbp circular plasmid and specific viruses that might influence their evolution through gene interactions.
  • Differences in defense mechanisms, such as restriction-modification systems, between Atabeyarchaeia and another Asgard archaea, Freyarchaeia, highlight how these systems can affect the relationship with MGEs and contribute to genetic diversity in these organisms.*
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  • Freshwater ecosystems are vital for global services, but human activities like urbanization, industry, and agriculture can negatively affect water quality.
  • This study analyzed water and biofilm samples from different sections of the Danube River to observe bacterial community diversity using advanced sequencing techniques.
  • Results indicated that biofilm communities had greater taxonomic diversity than planktonic communities and showed distinct variations based on habitat and river type, with urbanized areas hosting pollution-tolerant bacteria like Acinetobacter and Pseudomonas.
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  • The study aimed to identify patients with chronic hypoparathyroidism who either had adequate (AC) or not adequately controlled (NAC) disease, as poor control is linked to complications and increased mortality.
  • Researchers analyzed data from 337 patients across 16 Spanish hospitals to assess disease control through biochemical criteria and clinical wellness, finding that many patients were not adequately controlled.
  • Findings revealed that 45.9% to 63.1% of patients met the NAC criteria, with those who had dyslipidemia being at a greater risk, and NAC patients exhibited higher rates of associated comorbidities like chronic kidney disease and eye disorders compared to AC patients.
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Understanding fast pedestal dynamics and turbulent transport in the edge and scrape-off layer (SOL) plasma of spherical tokamaks is crucial for the design and operation of future fusion reactors. The alkali beam emission spectroscopy diagnostic technique offers a means to measure the absolute electron density radial profile and fluctuation amplitude in these regions. In this study, we demonstrate that injecting a sodium neutral beam radially into the plasma and analyzing the light emission from its 3p-3s atomic transition using near-orthogonal viewing angles allows for accurate measurement of the electron density profile and fluctuations in the National Spherical Torus Experiment (NSTX) Upgrade spherical tokamak.

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Recent experiments at the ASDEX Upgrade tokamak have provided the first ever measurements from the imaging heavy-ion beam probe. In this work, we show that the developed simulation framework can reproduce qualitatively the measurement's observed shape and position. Quantitatively, we demonstrate that the model reproduces, within the experimental uncertainties, the observed signal levels.

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Classically, chemokines coordinate leukocyte trafficking during immune responses; however, many chemokines have also been reported to possess direct antibacterial activity in vitro. Yet, the bacterial killing mechanism of chemokines and the biochemical properties that define which members of the chemokine superfamily are antimicrobial remain poorly understood. Here we report that the antimicrobial activity of chemokines is defined by their ability to bind phosphatidylglycerol and cardiolipin, two anionic phospholipids commonly found in the bacterial plasma membrane.

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Dozens of new antiviral systems have been recently characterized in bacteria. Some of these systems are present in eukaryotes and appear to have originated in prokaryotes, but little is known about these defense mechanisms in archaea. Here, we explore the diversity and distribution of defense systems in archaea and identify 2610 complete systems in Asgardarchaeota, a group of archaea related to eukaryotes.

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  • Scientists studied a group of tiny creatures called Asgard archaea to see how they affect soil ecosystems, especially in wetland soils.
  • They found two new genomes of these organisms and discovered that they can use different processes to break down substances.
  • The findings suggest that Asgard archaea could help with carbon cycling in the soil by breaking down materials without producing methane.
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Measurements of ion temperature profiles are required to assess the energy and particle transport processes in the Wendelstein 7-X stellarator. This device is equipped with a diagnostic alkali beam, which can be utilized to determine local impurity temperatures and densities by Charge Exchange Recombination Spectroscopy (CXRS). It could provide such profiles in the edge plasma, where other diagnostics are less efficient.

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Asgardarchaeota, commonly referred to as Asgard archaea, is a candidatus phylum-rank archaeal clade that includes the closest archaeal relatives of eukaryotes. Despite their prevalence in the scientific literature, the name Asgardarchaeota lacks nomenclatural validation. Here, we describe a novel high-quality metagenome-assembled genome (MAG), AB3033_2, proposed to serve as the nomenclatural type for the species Asgardarchaeum abyssi according to the rules of the SeqCode.

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Alkanes, single carbon methane to long-chain hydrocarbons (e.g. hexadecane and tetradecane), are important carbon sources to anaerobic microbial communities.

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Deterministic formation of membrane scission necks by protein machinery with multiplexed functions is critical in biology. A microbial example is M2 viroporin, a proton pump from the influenza A virus that is multiplexed with membrane remodeling activity to induce budding and scission in the host membrane during viral maturation. In comparison, the dynamin family constitutes a class of eukaryotic proteins implicated in mitochondrial fission, as well as various budding and endocytosis pathways.

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We conducted focus groups with staff from 5 community-based organizations (21 participants; 86% female, 52% Hispanic/Latino/a/x and 24% Mexican/Mexican American) between August and October 2021. Results highlighted community partner perceptions of practices congruent (e.g.

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Through a COVID-19 public health intervention implemented across sequenced research trials, we present a community engagement phased framework that embeds intervention implementation: (1) consultation and preparation, (2) collaboration and implementation, and (3) partnership and sustainment. Intervention effects included mitigation of psychological distress and a 0.28 increase in the Latinx population tested for SARS-CoV-2.

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Objective: To pilot test the COMmunity of Practice And Safety Support for Navigating Pain (COMPASS-NP) intervention for home care workers experiencing chronic pain.

Methods: Home care workers with chronic pain participated (n = 19; 2 groups) in a 10-week online group program focused on workplace safety and pain self-management. Primary outcomes were changes in pain interference with work and life.

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Background: Luteolin (3,4,5,7-tetrahydroxy flavone) is reported to strongly protect from acute carbon tetrachloride (CCl) -induced liver injury or fibrosis. Ferroptosis can be induced by hepatic injury, and contributes to liver fibrosis development. The exact functional mechanism underlying luteolin inhibition of hepatic injury and whether ferroptosis is involved are unclear.

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The measurement of the enterovirus and the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in sewage water is relevant in the early detection of the introduction or disappearance of these viruses in the ecosystem. We evaluated the co-circulation of the enteroviruses and SARS-CoV-2 in 81 sewage water samples collected between September 2021 and April 2023 from different regions of north and southeast Romania, at the border with Ukraine. We used, for the molecular detection of the pathogens, the multiplex real-time polymerase chain reaction (PCR) assay produced for respiratory samples and the Respiratory 2.

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