The Beyond Reality Image Collection (BRIC).

The Beyond Reality Image Collection (BRIC) is a set of 648 photos, some painted by an artist and some generated by artificial intelligence. Unlike previous photosets, the BRIC focused on nonrealistic visuals. This collection includes abstract and non-abstract paintings and nonrealistic photographs depicting objects, scenes, animals, humans, and fantastical creatures with varying degrees of unreal elements.

Validity and reliability of the Japanese version of the ACE tool for assessing evidence-based medicine competencies in medical practitioners and students: An evaluation in an online setting.

Introduction Evidence-based medicine (EBM) competency is crucial for healthcare professionals; however, validated tools to assess EBM skills in Japanese are scarce. This study aimed to develop and validate a Japanese version of the Assessing Competency in EBM (ACE) tool. Methods We translated the ACE tool into Japanese, following international standards, and distributed it online to 99 healthcare professionals and students.

Does the Brief Implicit Association Test measure semantic or affective valence representations?

Valence, the representation of a stimulus as positive or negative, is fundamental to conceptualizing attitudes and their empirical research. Valence has two potential representations: semantic and affective. The current line of studies investigates the degree to which the congruency effect of the Brief Implicit Association Test (BIAT), often used as an indirect evaluation measure, reflects affective or semantic aspects of valence.

Amoebic colitis insufficient to metronidazole monotherapy.

Amoebic colitis is a parasitic gastrointestinal disease caused by Entamoeba histolytica (E. histolytica). In Japan, metronidazole (MNZ) monotherapy is often used and most cases are effective.

Misfolding of transthyretin in vivo is controlled by the redox environment and macromolecular crowding.

Transthyretin (TTR) amyloidosis is a progressive disorder characterized by peripheral neuropathy, autonomic dysfunction, and cardiomyopathy. The precise mechanism by which TTR misfolds and forms fibrils in vivo remains incompletely understood, posing challenges to the development of effective therapeutics. In this study, we reveal that the recently identified nonnative pathological species of TTR (NNTTR), which is enriched in the plasma of ttr-val30met gene carriers, exhibits strong amyloidogenic properties, making it a promising therapeutic target.

The many faces of mimicry depend on the social context.

One of the richest and most powerful tools in social communication is the face. Facial expressions are a prominent way to convey high-dimensional, dynamic information, such as emotion, motivation, and intentions. Previous research has linked mimicry of facial expressions to positive human interaction (e.

Association between varus thrust and foot alignment and flexibility in knee osteoarthritis.

Background: Varus thrust (VT) is a frequently reported abnormal gait pattern in patients with medial knee osteoarthritis (KOA). VT is important to prevent KOA progression. However, there is no consensus on the relationship between VT and foot alignment and flexibility, although it has been reported that patients with KOA have pronated foot.

Assessing left atrial dysfunction in cardiac amyloidosis using LA-LV strain slope.

Aims: Transthyretin amyloid cardiomyopathy (ATTR-CM) is an infiltrative disease of the myocardium in which extracellular deposits of amyloid cause progressive cardiac impairment. We aimed to evaluate left atrial (LA) deformation and its association with left ventricular (LV) deformation using LA-LV strain loops in patients with ATTR-CM and patients with LV hypertrophy (LVH). We hypothesized that LA strain in ATTR-CM patients is abnormal and more independent of LV strain, compared to LVH patients.

Efficacy and safety of prostatic urethral lift according to preoperative urinary retention and prostate volume: A Japanese real-world multicenter data.

Objectives: Prostatic urethral lift (PUL) for benign prostatic hyperplasia has recently been initiated in Asia; therefore, few studies with real-world data have been reported. This study evaluated the efficacy and safety of PUL using Japanese real-world multicenter data.

Methods: Indications for PUL were based on relevant guidelines in Japan.

A review on optimization of Wilms tumour management using radiomics.

Background: Wilms tumour, a common paediatric cancer, is difficult to treat in low- and middle-income countries due to limited access to imaging. Artificial intelligence (AI) has been introduced for staging, detecting, and classifying tumours, aiding physicians in decision-making. However, challenges include algorithm accuracy, translation into conventional diagnosis, reproducibility, and reliability.

Magnetic diffusion in solar atmosphere produces measurable electric fields.

The efficient release of magnetic energy in astrophysical plasmas, such as during solar flares, can in principle be achieved through magnetic diffusion, at a rate determined by the associated electric field. However, attempts at measuring electric fields in the solar atmosphere are scarce, and none exist for sites where the magnetic energy is presumably released. Here, we present observations of an energetic event using the National Science Foundation's Daniel K.

Sphingosine-1-phosphate receptor 1-mediated odontogenic differentiation of mouse apical papilla-derived stem cells.

Background/purpose: Sphingosine-1-phosphate (S1P) exhibits receptor-mediated physiological effects by facilitating the differentiation of mesenchymal stem cells toward the osteoblast lineage. This study aimed to determine the effect of S1P on odontogenic differentiation of mouse immortalized stem cells of dental apical papilla (iSCAP) and assess the distribution of the S1P receptor 1 (S1PR1) in the apical papilla and the root canal wall of immature rat molars.

Materials And Methods: Immunostaining for S1PR1 was conducted at the apex of the rat mandibular first molar and within the root canal wall.

Learning interventions in the WHO Eastern Mediterranean region: supporting Member States to get prepared for better response to health emergencies in the region.

Background: The Eastern Mediterranean Region (EMR) faces numerous public health risks caused by biological, chemical, man-made, and natural hazards. This manuscript aimed to assess the multifaceted interventions and strategies used to strengthen the EMR's preparedness capacities to respond properly to current and upcoming health emergencies.

Objective: To address these challenges, it is crucial to implement comprehensive and robust strategic risk assessments and health emergency preparedness frameworks.

Interjoint Coordination at Different Squatting Speeds in Healthy Adults.

Background Squatting is commonly used in various settings to enhance muscle strength and performance. Both fast and slow squats have advantages as training to improve muscle function in the lower extremity muscles. Movement speed affects the variability of interjoint coordination and decreased variability can lead to overuse injuries owing to repetitive mechanical loading on the lower extremity joints.

Coordination of joint movement during gait in knee osteoarthritis: Insights from uncontrolled manifold analysis.

This study investigated the covariate structure of each segmental angle that stabilize the center of mass (COM) in the mediolateral and vertical directions in response to knee joint movement in individuals with knee osteoarthritis (KOA) using uncontrolled manifold (UCM) analysis. Twenty individuals with KOA and 13 healthy controls participated in this cross-sectional study. Kinematic and kinetic data were collected during level walking.