Publications by authors named "Ahmetagic"

Article Synopsis
  • The study focuses on the prevalence of antibiotic resistance in Brucella melitensis strains isolated from patients in Bosnia and Herzegovina, highlighting significant human health concerns due to brucellosis.
  • Among the 108 strains analyzed, a notable 84.3% showed resistance to trimethoprim-sulfamethoxazole in standard broth, while over 90% were resistant to azithromycin in multiple testing environments.
  • The findings suggest that alternative testing methods, like enriched broth, may improve understanding of antimicrobial resistance, indicating a need for further genomic studies to investigate the underlying mechanisms of resistance in these bacteria.
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Aims: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by ventricular dysfunction and ventricular arrhythmias (VA). Adequate arrhythmic risk assessment is important to prevent sudden cardiac death. We aimed to study the incremental value of strain by feature-tracking cardiac magnetic resonance imaging (FT-CMR) in predicting sustained VA in ARVC patients.

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Background: Dental documentation which includes main information about a patient and dental treatment provided is a very important asset of each dental office.

Objective: This research aims to analyze the way of fulfilling and keeping mandatory dental records and periodic reporting forms by doctors of dental medicine in the Federation of Bosnia and Herzegovina (FB&H).

Methods: The study was observational with a cross-sectional design using a questionnaire as a study tool.

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Article Synopsis
  • The study investigates COVID-19 transmission within Bosnian households, highlighting that the virus spreads through contact, droplets, and air, particularly in multi-generational family settings.
  • Conducted between March and December 2020, the research analyzed 25 index cases, all middle-aged men, leading to a significant 61.8% secondary transmission rate among 123 family members.
  • The findings reveal high intrafamilial transmission in Bosnia and Herzegovina, emphasizing the importance of preventive measures due to the serious impact, including hospitalizations and deaths.
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Introduction: Cytomegalovirus (CMV) infection is ubiquitous. It affects all age groups, and its clinical picture ranges from mild to severe, especially as a congenital infection in neonates.

Aim: To determine frequency of CMV infection in pregnant women in Tuzla Canton (TC) and the risk factors that lead to the infection.

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Introduction: Chronic HCV infection is chronic inflamatory liver disease caused by hepatitis C virus. Anti HCV prevalence among intravenous drug users (IVDU) is very high and it accounts 40% -90% (60%-90%) with the risk of 80% of developing the chronic infection.

Aim: The aims of this study were: a) to compare clinical characteristics of chronic HCV infection among IVDU and non-users population and to detect their impact to treatment outcome; b) to investigate the treatment efficacy comparing sustained viral response (SVR) in these two populations in Tuzla Canton.

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Risk assessment of central nervous system (CNS) infection patients is of key importance in predicting likely pathogens. However, data are lacking on the epidemiology globally. We performed a multicenter study to understand the burden of community-acquired CNS (CA-CNS) infections between 2012 and 2014.

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A measles outbreak with two epidemic waves involving 4649 probable and laboratory-confirmed cases was recorded in six out of ten cantons of the Federation of Bosnia and Herzegovina between February 2014 and April 2015. The majority of the patients had never received measles vaccination (3115/4649, 67.00%), and the vaccination status of another 23% was unknown (1066/4649).

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Recent culture-independent studies have enabled detailed mapping of human microbiome that has not been hitherto achievable by culture-based methods. DNA extraction is a key element of bacterial culture-independent studies that critically impacts on the outcome of the detected microbial profile. Despite the variations in DNA extraction methods described in the literature, no standardized technique is available for the purpose of microbiome profiling.

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Aim: To analyse clinical, laboratory and epidemiological characteristics of brucellosis in children in Bosnia and Herzegovina.

Methods: The study included 246 children aged 0-18 years, who were hospitalized in Clinics and Departments for Infectious Diseases in Tuzla, Sarajevo, Banja Luka, Zenica and Bihać in the period 2000-2013, in whom the diagnosis of brucellosis was established based on anamnestic data, clinical features and positive results from blood culture and/or positive results from one of the serological tests.

Results: In this period, a total of 2630 patients, 246 (9.

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Objective: The use of commercially available noninvasive markers for chronic hepatitis B (CHB) related fibrosis is not widely available in developing countries so clinicians in those countries frequently use free alternatives. We aimed to create an optimized algorithm for selection of patients with the highest probability for presence/absence of significant liver fibrosis and cirrhosis based on the use of multiple free scores.

Methods: We evaluated six free noninvasive markers for CHB related fibrosis against liver biopsy and selected the best thresholds for prediction/exclusion of significant fibrosis and cirrhosis in CHB patients.

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Introduction: More than three decades after recognition of acquired immunodeficiency syndrome (AIDS) in the United States, the pandemic of human immunodeficiency virus (HIV) infection has dramatically changed the global burden of disease.

Aim: The main goal of this research is retrospective analysis of epidemiological and clinical characteristics of 28 HIV infected patients, who were diagnosed and treated at the Clinic for Infectious Diseases in University Clinical Center Tuzla in the period from 1996 until the end of 2013.

Subjects And Methods: Retrospective analysis was performed using the medical records of 28 HIV-infected persons.

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Acute respiratory distress syndrome (ARDS) is a form of acute life threatening respiratory failure. In daily practice there is difficulty in diagnostic and therapeutic management of Acute respiratory distress syndrome (ARDS). We observed delay in diagnostic and therapeutic procedures in patients with clinical signs for the presence of severe respiratory disorders.

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Between January 2014 and the beginning of February 2015, the Federal Institute of Public Health in the Federation of Bosnia and Herzegovina has reported 3,804 measles cases. Notable transmission has been observed in three Central Bosnia Canton municipalities: Bugojno, Fojnica and Travnik. Most cases were unvaccinated 2,680 (70%) or of unknown vaccination status 755 (20%).

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Aim: To describe the first two cases of West Nile virus (WNV) neuroinvasive infections in Bosnia and Herzegovina.

Methods: At the Clinic for Infectious Diseases of the University Clinical Centre Tuzla, Bosnia and Herzegovina (BiH), specific screening for WNV infection was performed on patients with neuroinvasive diseases from 1 August to 31 October 2013. Serum samples were tested for the presence of WNV IgM and IgG antibodies using enzyme-linked immunosorbent assay (ELISA); positive serum samples were further analyzed by detection of WNV nucleic acid of two distinct lineages (lineage 1 and lineage 2) in sera by RT-PCR.

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Introduction: Acinetobacter baumannii is a frequent cause of infections in hospitals around the world, which is very difficult to control and treat. It is particularly prevalent in intensive care wards.

Aim: The main objective of the research was to establish the application of epidemiological monitoring of nosocomial infections (NIs) caused by A.

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Introduction: Intensive care units (ICUs) are associated with a greater risk of developing nosocomial infections (NIs) than other departments.

Aim: The aim of this study was to determine the rate, the site and causative organisms of NIs in the surgical ICU at University Clinical Center Tuzla.

Methods: All patients admitted to the surgical ICU were followed prospectively, for the development of NIs (January-December 2010).

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Aim: To determine the etiology of peritonitis, as well as the sensitivity of isolated bacteria to antibiotics.

Methods: Study was performed at the Surgical Clinic, Department of Anesthesiology and Reanimation, Department of Microbiology, Department of Clinical Pharmacology of University Clinical Centre (UCC) Tuzla. In a prospective study, starting from 1.

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Article Synopsis
  • The study compared ICU features, antimicrobial resistance patterns, infection control policies, and disease distribution across 88 ICUs in central Europe to Mid-West Asia.
  • Out of 749 patients assessed, pneumonia was the most common infection, with significant occurrences of hospital-acquired infections and a notable prevalence of multidrug-resistant pathogens like Enteric Gram-negatives and Acinetobacter spp.
  • Surveillance and management practices showed variability, with Turkey conducting more infection surveillance than Iran and Southeastern Europe, while Southeastern Europe had higher adherence to culture-guided antibiotic treatment.
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Introduction: Hospital-acquired Urinary tract infections make 35% of all the hospital-acquired infections, and about 80% of them are related to the catheterization of the urinary bladder.

Purpose: To determine clinical characteristics and dominant etiologic factors of Urinary Tract Infections associated with urinary catheter (C-UTIs).

Methods: Determined clinical characteristics of C-UTIs were prospectively analyzed on 38 hospitalized patients in the Clinic for Infectious Diseases at the University Clinical Centre Tuzla, from January 1(st) 2011 to December 31(st) 2011.

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Introduction: Clostridium difficile (C. difficile) is currently the leading cause of healthcare-associated diarrhea, but almost nothing is known about the extent of C. difficile infection (CDI) in Bosnia and Herzegovina.

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Conflict Of Interest: none declared.

Goal: The goal of the research is to determine the relationship between frequency and reporting of stab incidents, attitudes and knowledge about stab incidents and occupational risk for transmission of viral infection with HBV, HCV or HIV among health care professionals employed in primary health care.

Material And Methods: Conducted is prospective, cross-section study by questionnaires in 2012.

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Aim: To determine a predictive potential of biochemical and clinical parameters, including independent predictors of the therapeutic outcome in patients with H1N1 influenza.

Methods: In this retrospective study, 119 patients treated at the Clinic for Infectious Diseases in Tuzla in the period July 2009 to February 2010 were included. They were at the age of 1 month up to 80 years.

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Introduction: Bacterial meningitis is one of the most serious infectious diseases in childhood.

Aim: To identify the most common causes of bacterial meningitis in children in Tuzla Canton.

Patients And Methods: This is a retrospective study which included 140 children, aged from 1 month to 14 years, treated at the Clinic for Infectious Diseases Tuzla, in the period 1999-2009, who had clinical and laboratory parameters of bacterial meningitis.

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Introduction: The prevalence of human brucellosis in Bosnia and Herzegovina and the Tuzla Canton reached its peak in 2008, with a reported total of 994 cases within country, and with 104 cases within the Tuzla Canton.

Aim: to analyze the clinical and epidemiological features of human brucellosis in patients hospitalized at the University Clinical Center Tuzla during the period from 01/01/2000 till the 31/12/2010.

Methods: We retrospectively analyzed the clinical symptoms, the laboratory and X-ray findings, the treatments, and the course and outcome of the disease.

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