Effects of Brucea Javanica Oil Combined with Chemotherapy on Serum CYFRA21-1, Immune Mechanism and Prognosis in Lung Cancer Patients.

Objective: To investigate the effect of Brucea javanica Oil combined with chemotherapy on serum cytokeratin 19 fragment antigen 21-1 (CYFRA21-1), immune mechanism, and prognosis in patients with lung cancer and provide a reference for its clinical diagnosis and treatment.

Methods: This study involved 112 lung cancer patients from June 2019 to January 2022 at Shanghai Guanghua Hospital. They were randomly divided into two groups: control (chemotherapy only) and observation (chemotherapy + Brucea javanica oil emulsion).

Esports Physical Exercise/Performance Matrix 1.0 Country Factsheets: a protocol for national, regional, and global annual assessment study protocol.

This protocol helps evaluators gather current data and prepare annual assessments based on specific indicators to provide insights into physical activity among esports players and identify the challenges they face. This manuscript aims to develop a methodology for creating a standardized monitoring system to assess physical exercise and performance in esports players at national, regional, and global levels. This study protocol proposes 20 online sociodemographic indicators to help characterize participating countries and outline each country's demographic profile.

Marginal effects of economical development and university education on China's regular exercise population.

Objective: Although the regular exercise population is a key metric for gaging the success of China's fitness-for-all activities, effective policy approaches to increase mass sports participation remain unclear. Previous research suggests that GDP, educational attainment, sports resources, and meteorological conditions could influence regular exercise participation. Therefore, this study first analyzed the macro-level correlates influencing China's regular exercise population.

Factors driving FIFA world cup 2022 viewership ratings in mainland China: marketing outlooks for FIFA world cup 2026.

Introduction: The FIFA World Cup is not only the most lucrative athletic event globally, but it also functions as a platform for promoting peace owing to FIFA's new vision. Nevertheless, the determinants of TV viewership ratings, especially in the Chinese market, which is a critical revenue stream for FIFA TV broadcasting, are still unsolved. Using a distributional regression, this study aimed to quantify the dynamics of viewership ratings for the FIFA World Cup 2022 in mainland China.

12-week concurrent brisk walking and Taijiquan (Tai Chi) improve balance, flexibility, and muscular strength of Chinese older women.

Healthy aging is a global goal to enhance the quality of life for older persons. This study evaluated the benefits of 12-week concurrent brisk walking and Taijiquan. Healthy Chinese women aged 60 years and above were enrolled to the control (n = 26) and intervention (n = 25) groups.

China's new urban clusters strategy for coordinated economic growth: Evidence from the sports industry.

In 2014, the Chinese government unveiled the New Urbanization Plan and Document No. 46, which profoundly influenced the development trajectory of the regional economy and sports industry. Using the coupling coordination model, this study aimed to assess the development progress of the sports industry and urban clusters economy.

The Association Between the China's Economic Development and the Passing Rate of National Physical Fitness Standards for Elderly People Aged 60-69 From 2000 to 2020.

Objective: According to the seventh demographic census, China's elderly population reached 260 million, accounting for 18.7% of the total population, indicating that China is on the verge of transitioning from a relatively mild aging to a moderately aging society, and an aging society inevitably brings concerns about the elderly people's health. The purpose of this study was to better understand the effect of economic development on the physical fitness of the elderly people aged 60-69 in China during the first two decades of the twenty-first century, as well as to establish a correlation between China's gross domestic product (GDP) and changes in the elderly people's passing rate of national physical fitness standards.

Epithelial-mesenchymal transition and metastasis of colon cancer cells induced by the FAK pathway in cancer-associated fibroblasts.

Objective: The role and mechanism of tetrathiomolybdate (TM) in cancer-associated fibroblasts (CAFs) in colon cancer using three-dimensional (3D) culture were investigated, and the associations between the focal adhesion kinase (FAK) pathway and epithelial-mesenchymal transition (EMT) in CAFs were explored.

Methods: A 3D co-culture model of colon cancer LOVO cells with CAFs and normal fibroblasts (NFs) was established using Matrigel as a scaffold material. The differential expression of LOXL2 (lysyl oxidase-like 2) in the supernatant of CAFs and NFs was determined using ELISA, and expression levels of EMT-related proteins and FAK signaling pathway-related proteins were determined using western blot.

RRS1 silencing suppresses colorectal cancer cell proliferation and tumorigenesis by inhibiting G2/M progression and angiogenesis.

Colorectal cancer (CRC) is one of the most common malignancies worldwide. Ribosome biogenesis regulatory protein homolog (RRS1) is an essential factor involved in ribosome biogenesis, while its role in CRC remains largely unclear. Here, we found that RRS1 expression was significantly higher in CRC tissues compared with adjacent normal tissues.

Pharmacology of a traditional Chinese herb, Shuangren-Anshen capsule, in a hemorrhage mouse model by using an orthogonal array design.

Shuangren-Anshen capsule (SAC) is a traditional Chinese herb that was improved in our laboratory. An orthogonal experiment [L9(3)(4)] was used to optimize the extraction conditions. In vivo, a hemorrhage mouse model was established and the hemoglobin contents of normal control, model control, and treated mice were measured.