Investigation of gene Val158Met polymorphism in ovarian cancer.

Objective: Catechol-O-methyltransferase (COMT), the product of the gene, detoxifies the carcinogenic catechol estrogens. The aim of the present study was to examine the relationship between polymorphism and the risk of ovarian cancer.

Material And Methods: The study groups consist of 94 individuals as a patients group with ovarian cancer (n=47) and control group (n=47).