The association of polypoid growth pattern with lymph node involvement in endometrioid type endometrial adenocarcinoma.

Background: Tumor size is an independent predictor of lymph node metastasis and survival in the endometrioid type endometrial adenocarcinoma (EC). However, some of the ECs tend to grow towards the cavity in the polypoid pattern, which can reach very large sizes. In this study, we aimed to analyze the association of growing in the polypoid pattern of the tumor with the proportion of lymph node metastasis and extrauterine tumor spread.

The impact of uterine adenomyosis on the histopathological risk factors and survival in patients with endometrial adenocarcinoma.

A retrospective cohort study was performed on patients diagnosed with endometrial adenocarcinoma (EC) during a 9-year period to investigate the impact of co-existing adenomyosis on patients with EC. Group A included women with EC and adenomyosis and Group B EC cases without the presence of adenomyosis. Group A was more likely to have early-stage disease, tumours without deep myometrial invasion, low-grade tumours and tumours with negative lymphovascular space invasion when compared to Group B ( = 0.

Does cervicovaginal cytology have a role in the diagnosis and surveillance of endometrial adenocarcinoma?

Objective: To examine the role of cervicovaginal cytology in diagnoses and surveillance of the patients with endometrial carcinoma (EC).

Methods: Patients who underwent EC surgery that included a follow-up were reviewed retrospectively. The cohort was limited to the patients who had an available cervical cytology result within 12 months before the primary surgery took place.

Dedifferentiated endometrioid adenocarcinoma; clinicopathologic and immunohistochemical features of five cases.

Objective: Dedifferentiated endometrioid adenocarcinoma is a recently defined uterine tumor composed of low-grade endometrioid adenocarcinoma and undifferentiated carcinoma. Herein, we present clinicopathologic, morphologic, and immunohistochemical features of 5 cases of dedifferentiated endometrioid adenocarcinoma.

Material And Methods: All cases which were diagnosed as mixed endometrial adenocarcinoma (endometrioid+undifferentiated carcinoma) or dedifferentiated endometrioid adenocarcinoma between January 2008 and December 2014 were retrieved from the archives of our institution’s pathology department.

Computed tomography as a predictor of the extent of the disease and surgical outcomes in ovarian cancer.

Objectives: The aim of the present study is to determine the predictive value of Computed Tomography (CT), alone or in combination with serum CA-125 levels, for preoperative staging, detection of the extent of the disease, and surgical complications in patients with ovarian carcinoma.

Material And Methods: One hundred and fourteen patients diagnosed with ovarian carcinoma following an exploratory laparotomy with a preoperative CT scan, performed between January 2007 and June 2013, were enrolled in the study. Preoperative CT and intraoperative surgical findings were compared using 14 parameters and predictions of CT for gas-trointestinal, genitourinary, and cardiovascular complications.

Comparison of myometrial invasion and tumor free distance from uterine serosa in endometrial cancer.

Background: We aimed to investigate whether the tumor free distance (the distance between the uterine serosa and the tumor at its deepest point) is useful in surgical staging and in predicting prognosis.

Materials And Methods: Data from patients who underwent complete surgical staging for endometrial cancer between January 2006 and June 2011 were reviewed retrospectively. All demographic findings, surgical stages, histological type and grade, myometrial invasion, lymphovascular space invasion as well as abdominal cytology, cervical, adnexal, and omental involvement, and lymph node metastasis were recorded.

Do clinical and laboratory parameters effect maternal and fetal outcomes in pregnancies complicated with hemolysis, elevated liver enzymes, and low platelet count syndrome?

Objective: The aim of the study was to investigate whether the clinical features and laboratory parameters affect maternal and fetal outcomes in pregnancies complicated with HELLP syndrome.

Material And Methods: The medical records of pregnant patients complicated with HELLP syndrome were analyzed retrospectively between June 01, 2003 and June 01, 2010. The demographic data, medical history, admission symptoms, clinical and laboratory findings and recovery time were evaluated.

The diagnostic value of the Doppler ultrasonography in distinguishing the endometrial malignancies in women with postmenopausal bleeding.

Purpose: To investigate the diagnostic value of blood flow measurements in endometrial, myometrial and uterine vasculature by transvaginal Doppler ultrasonography in the differentiation of the neoplastic endometrial pathologies in women with postmenopausal bleeding.

Methods: 106 women who presented with postmenopausal bleeding were enrolled in a prospective cohort study. Endometrial thickness, pulsatility and resistance indices of the uterine, myometrial and endometrial vasculature, endometrial histopathology were measured by transvaginal Doppler sonography.

The positivity of Helicobacter pylori Stool Antigen in patients with Hyperemesis gravidarum.

Objective: We aimed to investigate the possible association between Helicobacter pylori infection and Hyperemesis gravidarum.

Material And Methods: Thirty-six pregnant women with Hyperemesis gravidarum with severe vomiting (more than 4 times a day), weight loss (≥3 kg), ketonuria and 36 pregnant women gestational age-matched, without nausea and vomiting attending our outpatient clinic for antenatal care were enrolled the study. Demographic data of the patients were registered.

Prospective clinical study of the association between plasma level of free IGF-1 and myometrial invasion min patients with endometrial adenocarcinoma.

Introduction: Endometrial carcinoma is a common malignancy of the female genital tract. There is a strong correlation between myometrial invasion and clinical prognosis. Increasing myometrial penetration is associated with an increasing risk of pelvic and para-aortic lymph node metastasis, adnexal metastasis, positive peritoneal cytology local vault recurrence, and hematogenous spread.

Residual and recurrent disease rates following LEEP treatment in high-grade cervical intraepithelial lesions.

Introduction: Loop electrosurgical excision procedure (LEEP) is a basic procedure in the conization performed on patients with CIN II/III. After excisional therapy, close follow up is essential for the earlier detection of residual and recurrent disease. The value of PAP-smear and HPV-DNA tests for investigation of residual and recurrent disease in patients diagnosed with high-grade intraepithelial lesion after LEEP treatment was purposed.

Primary malignant melanoma of the vagina.

Background: Primary vaginal melanoma is a rare, highly malignant, and poor prognostic disease.

Case: The 51-year-old patient with diagnosis of vaginal malignant melanoma was referred to our clinic. Since detection of pervasive brown lesions in the vagina total vaginectomy was performed.

Migration of an intrauterine device into the bladder: a rare case.

Introduction: Intrauterine device (IUD) application has been used for over 30 years and is a widely accepted contraception method among women because of its low-complication rates. The use of intrauterine devices may cause complications but migration of the IUD into an adjacent organ is rarely encountered.

Case: In the present report, we present a 26-year-old patient to whom IUD had been applied 2 years ago and whose examination performed due to pain and urinary complaints revealed migration of the uterine device into the bladder.

The prevalence and causes of sexual problems among premenopausal Turkish women.

Introduction: Sexual dysfunction in females is an important public health problem worldwide. It is suggested that sexual problems among women are more common than the number of diagnosed female sexual dysfunction (FSD) cases indicates.

Aim: To determine the frequency and causes of sexual problems among premenopausal and married women who attend primary healthcare facilities.

Huge leiomyoma in a woman with Down syndrome: a case report.

Background: For patients with Down syndrome, the reproductive period is becoming longer in relation to the increasing lifetime. Thus, the possibility of reproductive disorders is also increasing.

Case: A 37-year-old woman with trisomy 21 was hospitalized with uterine myomatosis, which was spreading to the umbilicus.

[Depression-anxiety and disability in the premenopausal and postmenopausal period].

Objective: The aim of the study is to compare levels of depression-anxiety and disability in premenopausal and postmenopausal women.

Method: The study was carried out with women between 45-55 years of age, living in the service area of a Mother-Child Health and Family Planning Center. Women who did not have a menstruation at least for one year were accepted as postmenopausal.