Introduction: Raynaud's phenomenon (RP) is a multifactorial disorder. If any underlying disease cannot be determined to be responsible for RP, then it is considered to be the primary RP (pRP). We aimed to investigate the differences between laboratory markers and impaired endothelial function in pRP.
View Article and Find Full Text PDFJ Coll Physicians Surg Pak
January 2021
Women are more likely than men to report physical and emotional exhaustion related to paid work. While this gender gap in job burnout is common in the literature, the mechanism is yet to be thoroughly understood. Our study offers a novel, and admittedly provocative, explanation for the difference in burnout between men and women.
View Article and Find Full Text PDFJ Coll Physicians Surg Pak
January 2021
Background And Objective: Pulmonary embolism (PE) is caused by some genetic factors for more than half patients. Paraoxonase 1 (PON1) has significant anti-oxidative and anti-inflammatory effects. According to our knowledge, there is no study researching the relation between PON 1 gene polymorphisms and PE in the literature.
View Article and Find Full Text PDFBackground And Objective: Pulmonary embolism (PE) is an important cardiovascular emergency with high mortality. There are still problems related to the diagnosis of PE and genetic research may play a key role on diagnosis as well as determining risk stratification. In the present study, the aim was to evaluate MTHFR C677T and A1298C polymorphisms that play a role on folate metabolism in PE patients.
View Article and Find Full Text PDFBlunt traumatic cardiac rupture is rare and associated with high mortality. The most popular theory of cardiac rupture after blunt thoracic trauma is rapid deceleration with disruption of the atria from their connections to the vena cava and pulmonary veins. In cases with both massive hemothorax and hemopericardium, injury can usually originate from the heart and/or major vessels.
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