CD39 expression on immune cells predicts methotrexate response in rheumatoid arthritis patients.

Background/aim: Rheumatoid arthritis (RA) is a chronic inflammatory disease affecting mostly small joints, such as hand and foot joints symmetrically with irreversible joint destruction. In this study, the relationship between CD39 expression and the treatment response of RA patients was examined to investigate its potential as a biomarker that demonstrates treatment response.

Materials And Methods: This study included 77 RA patients and 40 healthy controls (HC).

Acute effect of pseudoephedrine on macular microcirculation in healthy subjects: an optical coherence tomography angiography study.

Purpose: To quantitatively evaluate the acute effects of pseudoephedrine on the macular microvasculature using optical coherence tomography angiography (OCTA).

Study Design: Randomized placebo-controlled clinical study.

Methods: In this study, 60 right eyes of 60 healthy subjects were divided into 2 groups.

The effect of cycloplegia on the ocular biometry and intraocular lens power based on age.

Background: To investigate the effect of cycloplegia on the ocular biometry and intraocular lens (IOL) power in different age groups.

Methods: This cross-sectional study enrolled 240 right eyes of 240 healthy volunteers. Three groups were formed (range to years; group 1: 50-60, group 2: 30-40 and group 3: 10-20, respectively).

Effect of brimonidine tartrate 0.15% on scotopic pupil size and upper eyelid position: controlled trial.

Background: To evaluate the effect of brimonidine tartrate 0.15% ophthalmic solution on pupil size under scotopic condition and upper eyelid position.

Methods: This study comprised 72 eyes of 36 healthy subjects.

Effects of pamidronate administration on tooth eruption and mandibular growth in new born rats.

Purpose: Bisphosphonates are commonly used drugs in pediatric patients in the treatment of osteoporotic diseases and various types of cancers. The purpose of this study was to evaluate the effects of pamidronate administration on mandibular growth and tooth eruption in new born rats.

Materials And Methods: Forty Sprague Dawley rats were included in the study and divided into four groups as; 14th day pamidronate group, 30th day pamidronate group, 14th day control group and 30th day control group.

Isolated Anterior Lens Capsule Rupture Secondary to Blunt Trauma: Pathophysiology and Treatment.

A 25-year-old man suffered an isolated lens anterior capsular tear and mature cataract formation following blunt injury to his right eye. One week after the trauma, best-corrected visual acuity (BCVA) in the right eye was hand motion. B-scan ultrasonography showed that the lens posterior capsule was intact; no vitreous foreign body or retinal pathology were observed.

Comparison of Different Types of Complications in the Phacoemulsification Surgery Learning Curve According to Number of Operations Performed.

Objectives: To compare the differences in intraoperative complications rates by the number of resident-performed sequential phacoemulsification surgeries.

Materials And Methods: Preoperative and postoperative ophthalmological examination records and intraoperative data of 180 eyes of 140 patients who underwent cataract surgery by two residents between November 2009 and February 2012 were analyzed retrospectively. The data of 180 eyes were separated into 3 groups based on the number of operations performed: Group A (first 1-60 eyes), group B (61-120 eyes) and group C (last 121-180 eyes).

Correlation of Peripapillary Choroidal Thickness and Retinal Nerve Fiber Layer Thickness in Normal Subjects and in Patients with Glaucoma.

Purpose: This study was designed to compare the normal and glaucomatous eyes regarding retinal nerve fiber layer (RNFL) thickness and peripapillary choroidal thickness (PCT), and to investigate the correlation of RNFL thickness and PCT.

Subjects And Methods: Subjects were selected as a convenience sample of those from a tertiary referral practice of glaucoma. Thirty-two glaucomatous eyes were accepted as group 1; 30 normal eyes were accepted as group 2.

Spontaneous resolution of macular edema after silicone oil removal.

Aim: To investigate the macular changes in eyes filled with silicone oil (SO) and course of these changes after SO removal.

Methods: A retrospective optical coherence tomography scan review was conducted for twenty-four patients who underwent uncomplicated pars plana vitrectomy with SO tamponade for complex retinal detachments were detected with optical coherence tomography before, and one week, one month and three months after SO removal.

Results: Mean duration of SO tamponade was 3.

Retinal nerve fiber layer thickness changes in obstructive sleep apnea syndrome: one year follow-up results.

Aim: To investigate the retinal nerve fiber layer (RNFL) thickness changes in patients with obstructive sleep apnea syndrome (OSAS) for one year follow-up. To discuss the possibility of detecting tendency of glaucoma in this population by using spectral domain optical coherence tomography (3D-OCT-2000 Spectral domain).

Methods: After polysomnographic study, all subjects (64 OSAS patients and 40 controls) underwent detailed ophthalmological examination.

Choroidal thickness changes in patients with pseudoexfoliation syndrome.

To evaluate the choroidal thickness using spectral-domain optical coherence tomography (OCT) in patients with pseudoexfoliation syndrome (PXS) and to compare them with healthy controls. This observational comparative study consisted of 35 PXS patients and 35 age- and sex-matched control cases. The control cases had neither systemic nor ocular disease.

Comparison of the Retinomax hand-held autorefractor versus table-top autorefractor and retinoscopy.

Aim: To compare noncycloplegic and cycloplegic results of Retinomax measurements with findings achieved after cycloplegia using table-top autorefractor and retinoscopy.

Methods: The study included 127 patients (mean age 96.7mo, range 21 to 221).

Choroidal thickness in relation to sex, age, refractive error, and axial length in healthy Turkish subjects.

The aim of this study was to investigate the association between choroidal thickness (CT) and sex, age, refractive error (RE), and axial length in healthy subjects. This is a study of 154 eyes in 154 healthy subjects. CT measurements were performed by the same experienced technician using a spectral domain optical coherence tomography device.

Correlation of intraocular pressure with central corneal thickness in premature and full-term newborns.

Purpose: To evaluate the relation of central corneal thickness (CCT) and intraocular pressure (IOP) in preterm and full-term newborns.

Methods: The study included preterm infants who were admitted to the neonatal intensive care unit. A group of consecutive full-term newborns served as control group.

The effect of caffeine on choroidal thickness in young healthy subjects.

Background: To investigate the effect of oral caffeine intake on choroidal thickness using optical coherence tomography (OCT).

Methods: Eighteen otherwise healthy caffeine users and 18 controls were enrolled. All participants underwent OCT scanning with high-speed and resolution spectral-domain OCT device (3D OCT 2000, Topcon, Japan) at baseline, and 1 and 3 h following 200-mg oral caffeine intake in the study and after oral placebo in the control group.

The Effect of ND:YAG Laser Posterior Capsulotomy Size on Refraction, Intraocular Pressure, and Macular Thickness.

Purpose. The aim of this study is to examine the influence of capsulotomy size on, spherical equivalent (SE), intraocular pressure (IOP), and macular thickness. Materials and Methods.

Correlation of choroidal thickness with outer and inner retinal layers.

Background And Objective: To investigate the correlation of choroidal thickness with the outer and inner retinal layers.

Patients And Methods: A retrospective OCT scan review was conducted for healthy patients. Choroidal, outer retinal layer, and inner retinal layer thicknesses were measured at the fovea and 500 μm, 1,000 μm, and 1,500 μm temporal and nasal to the fovea.

Deep anterior lamellar keratoplasty using big-bubble technique for treatment of corneal stromal scars.

Purpose: To report the clinical outcomes of deep anterior lamellar keratoplasty (DALK) in patients with anterior corneal stromal scars associated with various etiologies.

Methods: A total of 79 eyes of 79 patients with corneal stromal scars sparing the Descemet membrane and the endothelium underwent DALK by using big-bubble technique. The main outcome measures of the study were the ability to successfully complete DALK, intraoperative and postoperative complications, best spectacle-corrected visual acuity, refraction, and graft clarity.

Comparison of conventional surgery and CO2 laser on intraoral soft tissue pathologies and evaluation of the collateral thermal damage.

Objective: The aim of the study was to compare conventional surgery with carbon dioxide (CO(2)) laser applied on oral soft tissue pathologies and to evaluate the effect of collateral thermal damage on histopathological diagnosis. Anesthesia need, postoperative pain, and intraoperative and postoperative complications were examined as part of the comparison.

Methods: Forty-three patients (32 female and 11 male) with a mean age of 54 (54 +/- 7.